Respiratory symptoms and occupational asthma in polyurethane foam production workers

dc.contributor.authorArzu YORGANCIOĞLU
dc.contributor.authorAyşın ŞAKAR
dc.contributor.authorTülay KESKİN
dc.contributor.authorGönül DİNÇ
dc.contributor.authorPınar ÇELİK
dc.date.accessioned2024-07-24T09:09:45Z
dc.date.available2024-07-24T09:09:45Z
dc.date.issued2002
dc.description.abstractToluene diisocyanate (TDI) and methylene diphenyl diisocyanate (MDI) and hexamethylene diisocyanate (HDI) are heavily used in the production of polyurethane foams. Occupational asthma (OA) is reported in approximately 5% of chronically exposed workers. This study aimed to evaluate the effects of isocyanate exposure on lung function in foam production workers in two different factories. Respiratory status was evaluated by a questionnaire modified from the occupational asthma report of ATS, physical examinaton and pulmonary function tests. Pulmonary function was evaluated using a mobile spirometer. 107 workers (1 female, 106 male) were included in the study. 77 of these were working in polyurethane foam production (49 in one, 28 in a second factory), 18 in a dye department and 12 (the control group) were working in the offices (mean age, 26, 30, 27.5and 31, respectively). All 3 groups were comparable in age and smoking habits. There were also no significant differences in frequency of respiratory signs and symptoms. However, pulmonary function tests showed significantly lower forced expiratory volume (FEV) and forced vital capacity (FVC) values in the polyurethane group. Of the 32 workers who had respiratory findings suggestive of asthma and who underwent peak expiratory flow (PEE) meter follow-up, 17 were found to show positive variability. Non-specific bronchial provocation tests were performed on these 17 workers and 3 (all of them were polyurethane pro-duction workers) were diagnosed as occupational asthma (3.89%). The results of the study indicate a need for the screening and monitoring of all polyurethane foam workers for isocyanate-related respiratory disorders and OA.
dc.identifier.issn1302-7786
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/22347
dc.language.isoeng
dc.subject[Fen > Tıp > Solunum Sistemi]
dc.titleRespiratory symptoms and occupational asthma in polyurethane foam production workers
dc.typeDiğer

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