Effects of nitric oxide-vascular endothelial growth factor systems in chick embryo cerebral vasculogenesis and angiogenesis; [Civciv Embriyosunda Serebral Vaskülogenezis ve Anjiogenezis Üzerine Nitrik Oxid-Vasküler Endotelyal Growth Faktörün Etkileri]
| dc.contributor.author | Temiz C. | |
| dc.contributor.author | Arslan M. | |
| dc.contributor.author | Sayın M. | |
| dc.contributor.author | Vatansever S. | |
| dc.contributor.author | Giray G. | |
| dc.contributor.author | Var A. | |
| dc.date.accessioned | 2025-04-10T11:14:44Z | |
| dc.date.available | 2025-04-10T11:14:44Z | |
| dc.date.issued | 2012 | |
| dc.description.abstract | Aim: Studies have depicted that nitric oxide and vascular endothelial growth factor systems have important biological effects in the development of vasculogenesis and angiogenesis. Material and Method: In this study; specific pathogen free white Leghorin type fertilised eggs were used. Result: Three main subgroups were designed regarding time points of 48; 72 and 80 hours of incubation. In 48 hours old embryos anjioblasts were seen; but no mature endothelial structure was present. In 72 hours old embryos endothelial maturation began. In the 80 hours there was a high level of endothelial maturation. In all 48 hours groups; tissue nitrite-nitrate concentrations were high but in the 72 hours group these values were higher than in the first group. In the 80 hours group; concentrations were lower and were statistically significant when compared to the 48 and 72 hours groups. Discussion: NO seems to be effective in early phases of vasculogenesis and angiogenesis; but its effect decreases with time. © 2012, Derman Medical Publishing. All rights reserved. | |
| dc.identifier.DOI-ID | 10.4328/JCAM.778 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.14701/50476 | |
| dc.publisher | Derman Medical Publishing | |
| dc.title | Effects of nitric oxide-vascular endothelial growth factor systems in chick embryo cerebral vasculogenesis and angiogenesis; [Civciv Embriyosunda Serebral Vaskülogenezis ve Anjiogenezis Üzerine Nitrik Oxid-Vasküler Endotelyal Growth Faktörün Etkileri] | |
| dc.type | Article |