Toll-like receptors and skin

dc.contributor.authorErmertcan, AT
dc.contributor.authorÖztürk, F
dc.contributor.authorGündüz, K
dc.date.accessioned2024-07-18T11:49:44Z
dc.date.available2024-07-18T11:49:44Z
dc.description.abstractToll-like receptors are important pattern recognition receptors which have key roles in both innate and adaptive immune responses. They are strongly associated with the pathogenesis of inflammatory and autoimmune diseases. Furthermore, Toll-like receptors have also been implicated in the pathogenesis of several skin diseases such as skin infections, psoriasis, acne vulgaris, lichen planus, Behcet's disease, leprosy, syphilis, Lyme disease, atopic dermatitis and allergic contact dermatitis, mycosis fungoides, non-melanoma skin cancers and melanoma. In this manuscript, the structure and functions of Toll-like receptors in immune responses, their impact on skin diseases and recent advances on therapeutic usage have been reviewed.
dc.identifier.issn0926-9959
dc.identifier.other1468-3083
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/4251
dc.language.isoEnglish
dc.publisherWILEY
dc.subjectBASAL-CELL CARCINOMA
dc.subjectPROMOTER POLYMORPHISM
dc.subjectHUMAN KERATINOCYTES
dc.subjectTOPICAL IMIQUIMOD
dc.subjectACTIVATION
dc.subjectEXPRESSION
dc.subjectINNATE
dc.subjectTLR9
dc.subjectRECOGNITION
dc.subjectASSOCIATION
dc.titleToll-like receptors and skin
dc.typeReview

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