Changes of plasma magnesium concentrations in peroperative magnesium administration for analgesia; [Peroperatif analjezi amaçli magnezyum uygulamasinda plazma magnezyum düzeyi degişiklikleri]

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dc.contributor.authorTekin I.
dc.contributor.authorAlincak H.
dc.contributor.authorOk G.
dc.contributor.authorErbüyün K.
dc.date.accessioned2024-07-22T08:25:24Z
dc.date.available2024-07-22T08:25:24Z
dc.date.issued2001
dc.description.abstractWe evaluated the effect of peroperative magnesium replacement on analgesic consumption and changes of plasma magnesium (Mg) concentrations peroperatively. We administered % 0.9 NaCl (Group K, n=20) and MgSO4 (Group M, n=20) bolus and infusion peroperative and untill the end of the postoperative 6th hour in patients undergoing total hysterectomy. Fentanyl 3 μg/kg, propofol 2 mg/kg and vecuronium 0.1 mg/kg had been given in anesthesia induction and continued with % 60 N2O+O2 and 1 % sevoflurane after tracheal intubation into the both groups. Fentanyl 2 μg/kg had been added when heart rate (HR) and mean arterial pressure (MAP) were 15-20 % greater than basal values in all patients. Plasma Mg concentration, MAP and HR were recorded preoperatively, after induction and incision, on postoperative 30. min., 3-6th hours. In addition VAS and sedation scores were recorded postoperatively. Patient controlled analgesia with fentanyl was used for postoperative analgesia. Total fentanyl dose, demand and delivery were recorded. Intraoperative fentanyl consumption was decreased by 40 % in Group M. Postoperative fentanyl consumption was not different between two groups. VAS scores decreased on the 3th and 6th hours in comparison to 30th min postoperatively in Group M. Blood magnesium concentrations were decreased after preoperative period in Group K, and all recordings were higher than preoperative values in Group M. In conclusion, we believed that blood magnesium concentration decreases peroperatively in total hysterectomies, and that the doses we choose were safe despite increased plasma Mg concentration.
dc.identifier.issn10165150
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/20408
dc.language.isoTurkish
dc.subjectfentanyl
dc.subjectmagnesium
dc.subjectmagnesium sulfate
dc.subjectnitrous oxide
dc.subjectoxygen
dc.subjectpropofol
dc.subjectsevoflurane
dc.subjectvecuronium
dc.subjectabdominal hysterectomy
dc.subjectadult
dc.subjectaged
dc.subjectanesthesia induction
dc.subjectarticle
dc.subjectbolus injection
dc.subjectclinical article
dc.subjectclinical trial
dc.subjectcontrolled clinical trial
dc.subjectcontrolled study
dc.subjectdisease course
dc.subjectdrug infusion
dc.subjectdrug use
dc.subjectfemale
dc.subjectheart rate
dc.subjecthuman
dc.subjecthypertension
dc.subjectinhalation anesthesia
dc.subjectmagnesium blood level
dc.subjectmean arterial pressure
dc.subjectpain assessment
dc.subjectpatient controlled analgesia
dc.subjectperoperative care
dc.subjectpostoperative pain
dc.subjectpostoperative period
dc.subjectsedation
dc.subjectskin incision
dc.subjectsupplementation
dc.subjecttachycardia
dc.subjectvisual analog scale
dc.titleChanges of plasma magnesium concentrations in peroperative magnesium administration for analgesia; [Peroperatif analjezi amaçli magnezyum uygulamasinda plazma magnezyum düzeyi degişiklikleri]
dc.typeArticle

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