Synthesis and characterization of cerium- and gallium-containing borate bioactive glass scaffolds for bone tissue engineering

dc.contributor.authorDeliormanli, AM
dc.date.accessioned2024-07-18T11:54:22Z
dc.date.available2024-07-18T11:54:22Z
dc.description.abstractBioactive glasses are widely used in biomedical applications due to their ability to bond to bone and even to soft tissues. In this study, borate based (13-93B3) bioactive glass powders containing up to 5 wt% Ce2O3 and Ga2O3 were prepared by the melt quench technique. Cerium (Ce+3) and gallium (Ga+3) were chosen because of their low toxicity associated with bacteriostatic properties. Bioactive glass scaffolds were fabricated using the polymer foam replication method. In vitro degradation and bioactivity of the scaffolds were evaluated in SBF under static conditions. Results revealed that the cerium-and gallium-containing borate glasses have much lower degradation rates compared to the bare borate glass 13-93B3. In spite of the increased chemical durability, substituted glasses exhibited a good in vitro bioactive response except when the Ce2O3 content was 5 wt%. Taking into account the high in vitro hydroxyapatite forming ability, borate glass scaffolds containing Ce+3 and Ga+3 therapeutic ions are promising candidates for bone tissue engineering applications.
dc.identifier.issn0957-4530
dc.identifier.other1573-4838
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/6299
dc.language.isoEnglish
dc.publisherSPRINGER
dc.subjectIN-VITRO EVALUATION
dc.subjectCONTROLLABLE DEGRADATION
dc.subjectOXIDE NANOPARTICLES
dc.subjectSILICATE 45S5
dc.subjectHYDROXYAPATITE
dc.subjectBOROSILICATE
dc.subjectCONVERSION
dc.subjectSURFACE
dc.subjectPROLIFERATION
dc.subjectRESORPTION
dc.titleSynthesis and characterization of cerium- and gallium-containing borate bioactive glass scaffolds for bone tissue engineering
dc.typeArticle

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