Does Microwave Exposure at Different Doses in the Pre/Postnatal Period Affect Growing Rat Bone Development?

Simple item page
dc.contributor.authorKaradayi, AA
dc.contributor.authorSarsmaz, HY
dc.contributor.authorÇigel, A
dc.contributor.authorEngiz, BK
dc.contributor.authorÜnal, NA
dc.contributor.authorÜrkmez, SS
dc.contributor.authorGürgen, SG
dc.date.accessioned2024-07-18T12:03:33Z
dc.date.available2024-07-18T12:03:33Z
dc.description.abstractEffects of pre/postnatal 2.45 GHz continuous wave (CW), Wireless -Fidelity (Wi-Fi) Microwave (MW) irradiation on bone have yet to be well defined. The present study used biochemical and histological methods to investigate effects on bone formation and resorption in the serum and the tibia bone tissues of growing rats exposed to MW irradiation during the pre/postnatal period. Six groups were created: one control group and five experimental groups subjected to low-level different electromagnetic fields (EMF) of growing male rats born from pregnant rats. During the experiment, the bodies of all five groups were exposed to 2.45 GHz CW-MW for one hour/day. EMF exposure started after fertilization in the experimental group. When the growing male rats were 45 days old in the postnatal period, the control and five experimental groups' growing male and maternal rats were sacrificed, and their tibia tissues were removed. Maternal rats were not included in the study. No differences were observed between the control and five experimental groups in Receptor Activator Nuclear factor-kB (RANK) biochemical results. In contrast, there was a statistically significant increase in soluble Receptor Activator of Nuclear factor-kB Ligand (sRANKL) and Osteoprotegerin (OPG) for 10 V/m and 15 V/m EMF values. Histologically, changes in the same groups supported biochemical results. These results indicate that pre/postnatal exposure to 2.45 GHz EMF at 10 and 15 V/m potentially affects bone development.
dc.identifier.issn0862-8408
dc.identifier.other1802-9973
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/9183
dc.language.isoEnglish
dc.publisherACAD SCIENCES CZECH REPUBLIC, INST PHYSIOLOGY
dc.subjectKAPPA-B LIGAND
dc.subjectPULSED ELECTROMAGNETIC-FIELDS
dc.subjectNECROSIS-FACTOR RECEPTOR
dc.subjectOSTEOCLAST DIFFERENTIATION
dc.subjectMESSENGER-RNA
dc.subject1800 MHZ
dc.subjectOSTEOPROTEGERIN
dc.subjectACTIVATOR
dc.subjectRANK
dc.subjectOSTEOPOROSIS
dc.titleDoes Microwave Exposure at Different Doses in the Pre/Postnatal Period Affect Growing Rat Bone Development?
dc.typeArticle

Files

Collections

Web of Science Koleksiyonu