Biodistribution of Whey Protein Labeled with Tc-99m on Experimental Animals

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dc.contributor.authorMert AKINLI
dc.contributor.authorVolkan TEKİN
dc.contributor.authorFazilet Zümrüt BİBER MÜFTÜLER
dc.contributor.authorGökçen TOPAL
dc.contributor.authorYasemin PARLAK
dc.contributor.authorGül GÜMÜŞLER
dc.contributor.authorUğur AVCIBAŞI
dc.date.accessioned2024-07-24T09:13:54Z
dc.date.available2024-07-24T09:13:54Z
dc.date.issued2021
dc.description.abstractIn this study, whey protein was radiolabeled with $Tc-^{99m}$ using the SnCl2 reduction method. The paper electrophoresis technique was done in the radiochromatography studies. SF (saline solution) was used as a suitable mobile phase. At the same time, the labeling yield of ${}^{99m}Tc$WHEY was found to be about 95%. Then, lipophilicity and stability studies were carried out, respectively. Finally, imaging and biodistribution studies were completed using Albino Wistar Rats. In vivo studies showed that ${}^{99m}Tc$WHEY was accumulated in the breast, the ovaria and the pancreas. In conclusion, all results showed that ${}^{99m}Tc$WHEY may be helpful in the diagnosis of the breast, the ovaria and the pancreas in the future.
dc.identifier.DOI-ID10.15671/hjbc.656021
dc.identifier.issn1303-5002
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/25657
dc.language.isoeng
dc.titleBiodistribution of Whey Protein Labeled with Tc-99m on Experimental Animals
dc.typeAraştırma Makalesi

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