The Effects of an 8-week Walking Program on Serum Lipids, Circulation Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 in Post-menopausal Women

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dc.contributor.authorBüyükyazi, G
dc.contributor.authorUlman, C
dc.contributor.authorTaneli, F
dc.contributor.authorAksoy, D
dc.contributor.authorTikiz, H
dc.contributor.authorAri, Z
dc.date.accessioned2024-07-18T11:39:22Z
dc.date.available2024-07-18T11:39:22Z
dc.description.abstractPurpose: To examine the effects of an 8-week walking program on serum lipids, circulation matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in post-menopausal women. Method: Body weight, percent body fat, body mass index, estimated maximal oxygen consumption, blood lipids, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1 concentrations were assessed and their matrix metalloproteinase-9/tissue inhibitor of metalloproteinase-1 molar ratios were calculated in exercise (n=12) and control (n=12) groups. Exercise group completed an eight-week walking program at moderate (similar to 6.29 +/- 0.15km/h; similar to 62% maximum heart rate reserve) intensity. Results: Significant changes in estimated maximal oxygen consumption, systolic and diastolic blood pressures, body weight, and body mass index (p<.05) were determined in exercise group. However, there were no significant changes in the measured blood lipids (triglyceride, cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol), matrix metalloproteinase-9, and tissue inhibitor of metalloproteinase-1 concentrations, and matrix metalloproteinase-9/tissue inhibitor of metalloproteinase-1 molar ratio of exercise group, except for a nearly significant change in tissue inhibitor of metalloproteinase-1 level (p=.092). We determined no significant changes in any of the measured parameters in control group. Conclusion: Despite its protective effects against coronary heart disease risks, the duration and intensity of this program is not sufficient to cause significant changes in blood lipids, matrix metalloproteinase-9, and tissue inhibitor of metalloproteinase-1 concentrations. A higher-intensity, longer-duration program accompanied with diet is proposed.
dc.identifier.issn0250-4685
dc.identifier.other1303-829X
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/1574
dc.language.isoEnglish
dc.publisherWALTER DE GRUYTER GMBH
dc.subjectCORONARY-HEART-DISEASE
dc.subjectC-REACTIVE PROTEIN
dc.subjectPHYSICAL-ACTIVITY
dc.subjectCARDIOVASCULAR-DISEASE
dc.subjectMATRIX METALLOPROTEINASES
dc.subjectOXIDATIVE STRESS
dc.subjectNITRIC-OXIDE
dc.subjectEXERCISE INTERVENTION
dc.subjectREPLACEMENT THERAPY
dc.subjectARTERY DISEASE
dc.titleThe Effects of an 8-week Walking Program on Serum Lipids, Circulation Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 in Post-menopausal Women
dc.typeArticle

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