Effects of Se, Cu and Se + vitamin E deficiency on the activities of CuZnSOD, GSH-Px, CAT and LPO levels in chicken erythrocytes
| dc.contributor.author | Bozkaya L.A. | |
| dc.contributor.author | Oand̈ztuand̈rk-Uand̈rek R. | |
| dc.contributor.author | Aydemir T. | |
| dc.contributor.author | Tarhan L. | |
| dc.date.accessioned | 2025-04-10T11:18:10Z | |
| dc.date.available | 2025-04-10T11:18:10Z | |
| dc.date.issued | 2001 | |
| dc.description.abstract | Antioxidant enzymes and vitamins provide a defence against the damage of cells by reactive oxygen species in living systems. The effect of Cu, Se and vitamin E deficiencies on the antioxidant enzyme activities and lipid peroxide levels of chicken erythrocytes were investigated during 6 weeks of a depletion diet. CuZnSOD activity and the plasma Cu level of the Cu-deficient group which was fed a diet containing 0.2 mg Cu kg -1 were reduced to 62 and 71% respectively. GSH-Px activity of the Se-deficient group was decreased by 46% but by 21% in the Cu-deficient group. CAT activity values of Se- and Cu-deficient groups were increased by 28 and 10% respectively. The maximum increase of LPO levels in erythrocyte membranes was observed as 32% for the Se + E-deficient group. The LPO level of the Cu-deficient group which had decreased CuZnSOD and GSH-Px activity, was also observed to be significantly increased when compared with the controls (p < 0.05). Copyright © 2001 John Wiley & Sons, Ltd. | |
| dc.identifier.DOI-ID | 10.1002/cbf.906 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.14701/53238 | |
| dc.title | Effects of Se, Cu and Se + vitamin E deficiency on the activities of CuZnSOD, GSH-Px, CAT and LPO levels in chicken erythrocytes | |
| dc.type | Article |