Pulmonary hypertension in patients with chronic renal failure

Simple item page
dc.contributor.authorHavlucu, Y
dc.contributor.authorKursat, S
dc.contributor.authorEkmekci, C
dc.contributor.authorCelik, P
dc.contributor.authorSerter, S
dc.contributor.authorBayturan, O
dc.contributor.authorDinc, G
dc.date.accessioned2024-07-18T12:02:33Z
dc.date.available2024-07-18T12:02:33Z
dc.description.abstractBackground: Many etiologies causing pulmonary hypertension (PH) have been reported, and one of the background disease seen with patients with PH is chronic renal failure (CRF); however, the pathogenesis of PH in this group of patients is not explained satisfactorily. Objectives: The aims of this study were to evaluate the incidence of unexplained PH among patients with CRF and to suggest possible etiologic factors. Methods: Two hundred and eleven patients with CRF were evaluated and the ones who have comorbid conditions that cause PH were excluded. Pulmonary arterial pressure (PAP) and cardiac functions were evaluated by Doppler echocardiography. Arteriovenous fistula (AVF) flow was measured by Doppler sonography. The patients were followed for at least 6 months. Results: Forty-eight CRF patients (20 males, 28 females) were included: 23 were predialysis patients, and 25 patients received hemodialysis via AVF. Patients were followed for 7.5 +/- 1.01 months. Systolic PAP>35 mm Hg was found in 56% (14/25) of patients receiving hemodialysis (36.8 +/- 10.7 mm Hg) and in 39.1% (9/23) of predialysis patients ( 29.5 +/- 9.5 mm Hg). The parathyroid hormone level, cardiac output values and CRF duration were found to be increased in patients with elevated systolic PAP (p < 0.05). AVF flow and AVF duration were positively correlated with systolic PAP in patients receiving hemodialysis (p < 0.05). There was a negative correlation between systolic PAP and residual urine volume (p < 0.05). AVF compression in hemodialysis patients decreased systolic PAP from 36.8 +/- 10.7 to 32.8 +/- 10.5 mm Hg. Systolic PAP values were increased at the end of the study in the predialysis group, whereas they were decreased at the end of the follow-up in the hemodialysis group (36.9 +/- 10.5 and 32.04 +/- 10.5 mm Hg, respectively). Conclusions: This study demonstrates a high incidence of PH among patients with CRF.CRF duration, AVF flow, parathyroid hormone level and cardiac output may be involved in the pathogenesis of PH. The effective hemodialysis and dry weight reduction decreased systolic PAP values. Copyright (c) 2007 S. Karger AG, Basel
dc.identifier.issn0025-7931
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/8520
dc.language.isoEnglish
dc.publisherKARGER
dc.subjectSOFT-TISSUE CALCIFICATION
dc.subjectCHRONIC DIALYSIS PATIENTS
dc.subjectHEART-FAILURE
dc.subjectHEMODIALYSIS
dc.subjectREPRODUCIBILITY
dc.subjectDISEASE
dc.titlePulmonary hypertension in patients with chronic renal failure
dc.typeArticle

Files

Collections

Web of Science Koleksiyonu