Evaluation of Subclinical Multiple Sclerosis Patients Using Pattern Visual Evoked Potentials and Visual Field Test
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Objectives: The aim of this study was to evaluate subclinical multiple sclerosis (MS) patients with normal visual acuity using pattern visual evoked potentials (PVEP) test and central 30-2 threshold visual field (VF) test. Materials and Methods: A total of 60 patients, 30 of which had a definitive MS diagnosis and 30 who were healthy volunteers, were included in the study. The participants were divided into the following three groups: Group 1 -optic neuritis (+) MS patients, Group 2 -optic neuritis (-) MS patients, and Group 3 - control group. Using white on white perimetry, SITA FAST central 30-2 threshold VF tests and 1 degrees-0.3 degrees PVEP measurements were performed. MD, PSD, p100 latency (ms), p100 amplitude (mu V), and central 0-10 degrees, 0-20 degrees, 0-30 degrees, 10-20 degrees, 10-30 degrees, 20-30 degrees retina sensitivities (db) were evaluated in all groups. Results: There was a significant difference in all parameters between Group 1 and Group 3 (p<0.05). There was a significant difference in p100 latency 1 degrees-0.3 degrees, p100 amplitude 0.3 degrees, central 0-30 degrees, 10-30 degrees, 20-30 degrees between Group 2 and Group 3 (p<0.05). There was no significant difference in the parameters except for p100 amplitude 1 degrees between Group 1 and Group 2 (p>0.05). Conclusion: The evaluation of PVEP and central 30 degrees VF can be used to monitor disease prognosis in subclinical MS patients.