The effect of levosimendan on weaning from cardiopulmonary bypass and early hemodynamic parameters in patients with compromised left ventricular function; [Kötü sol ventrikül fonksiyonlu hastalarda levosimendanin kardiyopulmoner baypastan ayrilma ve erken dönem hemodinamik parametreler Üzerine etkileri]

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dc.contributor.authorÖztürk T.
dc.contributor.authorŞirin H.
dc.contributor.authorToprak V.
dc.contributor.authorErtan Y.
dc.contributor.authorCerrahoǧlu M.
dc.date.accessioned2024-07-22T08:23:09Z
dc.date.available2024-07-22T08:23:09Z
dc.date.issued2006
dc.description.abstractIn this study we determined the effects of levosimendan on hemodynamic parameters during weaning from cardiopulmonary bypass (CPB) and in the early postoperative period in patients with compromised left ventricular-function. Charts of 18 patients with an ejection fraction of ≤30 % who underwent elective coronary artery bypass (CABG) surgery were reviewed. Eight (Group L) had received a loading dose of levosimendan (6 μg kg-1) within 10 minutes after removal of the cross clamp, followed by an infusion (0.1 mcg kg-1 min-1). Control patients (n=10, Group C) received dopamine, dobutamine or adrenaline. Hemodynamic parameters during the early postoperative period were compared. Cardiac index (CI) was significantly higher than baseline in both groups at one and six hours after removal of the cross clamp (p<0.05). CI was significantly greater, and SVRI and PVRI were significantly lower, in Group L at both one and six hours (p<0.001). In conclusion, the use of levosimendan was associated with more favourable hemodynamic effects in patients with compromised left ventricular function during weaning from CPB and in the early postoperative period after CABG surgery.
dc.identifier.issn13055550
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19387
dc.language.isoTurkish
dc.subjectadrenalin
dc.subjectamiodarone
dc.subjectaritmal
dc.subjectdiazepam
dc.subjectdobutamine
dc.subjectdopamine
dc.subjectetomidate
dc.subjectfentanyl
dc.subjectlevosimendan
dc.subjectlidocaine
dc.subjectmidazolam
dc.subjectmidazolam maleate
dc.subjectsevoflurane
dc.subjectunclassified drug
dc.subjectvecuronium
dc.subjectadult
dc.subjectaged
dc.subjectartery clamp
dc.subjectcardiopulmonary bypass
dc.subjectcontrolled study
dc.subjectcoronary artery bypass surgery
dc.subjectdrug effect
dc.subjectdrug infusion
dc.subjectelective surgery
dc.subjectfemale
dc.subjectheart ejection fraction
dc.subjectheart index
dc.subjectheart left ventricle performance
dc.subjecthemodynamic parameters
dc.subjecthuman
dc.subjectloading drug dose
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmedical record review
dc.subjectpostoperative period
dc.subjectreview
dc.subjectweaning
dc.titleThe effect of levosimendan on weaning from cardiopulmonary bypass and early hemodynamic parameters in patients with compromised left ventricular function; [Kötü sol ventrikül fonksiyonlu hastalarda levosimendanin kardiyopulmoner baypastan ayrilma ve erken dönem hemodinamik parametreler Üzerine etkileri]
dc.typeReview

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