Prevalence of Vitamin D Deficiency and Hypervitaminosis D Among Adult Patients Admitted to the Tertiary Care Hospitals in Turkey
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Date
2022
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Abstract
Objective: Vitamin D deficiency is a common health problem around the world. This study aimed to
evaluate the nationwide prevalence of vitamin D status in tertiary care hospitals in Turkey.
Methods: Retrospectively, the data on vitamin D levels from 33 tertiary care hospitals’ clinical biochemistry
laboratories around Turkey between January and December were collected.
Results: In total, 706 434 serum samples from adult subjects (female/male: 469 028/237 406;
66.4%/33.6%) were included. While vitamin D levels were sufficient in 20.3% (n = 14 222), they were
insufficient in 21.9% (n = 154 360) and deficient in 57.8% (n = 408 882).
We observed the highest rates of deficiency in those aged between 18 and 29 years (62.9%, n = 70
235) and lowest rates between 60 and 69 years (52.3%, n = 61 121) and between 70 and 79 years
(52.3%, n = 32 397). Hypervitaminosis D was detected in 5.5% of adult subjects; highest rates of
hypervitaminosis D were observed in those who were over 80 years (6.6%) and 70-79 years (6.5%)
and the lowest in 18-29 years (2.8%).
Discussion: In this cohort, over half of the subjects admitted to the tertiary care hospitals in Turkey
had vitamin D deficiency and required vitamin D supplementation. The elderly population had the
lowest prevalence of vitamin D insufficiency and the highest prevalence of hypervitaminosis D.