Antibiotic associated diarrhea in outpatient pediatric antibiotic therapy

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dc.contributor.authorBasaranoglu, ST
dc.contributor.authorKaraaslan, A
dc.contributor.authorSali, E
dc.contributor.authorÇiftçi, E
dc.contributor.authorAydin, ZGG
dc.contributor.authorKocabas, BA
dc.contributor.authorKaya, C
dc.contributor.authorBayturan, SS
dc.contributor.authorKara, SS
dc.contributor.authorÇiftdogan, DY
dc.contributor.authorÇay, Ü
dc.contributor.authorAktürk, HG
dc.contributor.authorÇelik, M
dc.contributor.authorOzdemir, H
dc.contributor.authorSomer, A
dc.contributor.authorDiri, T
dc.contributor.authorYazar, AS
dc.contributor.authorSütçü, M
dc.contributor.authorTezer, H
dc.contributor.authorOncel, EK
dc.contributor.authorKara, M
dc.contributor.authorÇelebi, S
dc.contributor.authorParlakay, AÖ
dc.contributor.authorKarakaslilar, S
dc.contributor.authorArisoy, ES
dc.contributor.authorTanir, G
dc.contributor.authorKara, TT
dc.contributor.authorDevrim, I
dc.contributor.authorErat, T
dc.contributor.authorAykaç, K
dc.contributor.authorKaba, Ö
dc.contributor.authorGüven, S
dc.contributor.authorYesil, E
dc.contributor.authorYilmaz, AT
dc.contributor.authorDurmus, SY
dc.contributor.authorÇaglar, I
dc.contributor.authorGünay, F
dc.contributor.authorÖzen, M
dc.contributor.authorDinleyici, EÇ
dc.contributor.authorKara, A
dc.date.accessioned2024-07-18T12:08:19Z
dc.date.available2024-07-18T12:08:19Z
dc.description.abstractBackgroundAntibiotic-associated diarrhea is one of the most frequent side effects of antimicrobial therapy. We assessed the epidemiological data of antibiotic-associated diarrhea in pediatric patients in our region.MethodsThe prospective multi-center study included pediatric patients who were initiated an oral antibiotic course in outpatient clinics and followed in a well-established surveillance system. This follow-up system constituded inclusion of patient by the primary physician, supply of family follow-up charts to the family, passing the demographics and clinical information of patient to the Primary Investigator Centre, and a close telephone follow-up of patients for a period of eight weeks by the Primary Investigator Centre.ResultsA result of 758 cases were recruited in the analysis which had a frequency of 10.4% antibiotic-associated diarrhea. Among the cases treated with amoxicillin-clavulanate 10.4%, and cephalosporins 14.4% presented with antibiotic-associated diarrhea. In the analysis of antibiotic-associated diarrhea occurrence according to different geographical regions of Turkey, antibiotic-associated diarrhea episodes differed significantly (p = 0.014), particularly higher in The Eastern Anatolia and Southeastern Anatolia. Though most commonly encountered with cephalosporin use, antibiotic-associated diarrhea is not a frequent side effect.ConclusionThis study on pediatric antibiotic-associated diarrhea displayed epidemiological data and the differences geographically in our region.
dc.identifier.other1471-2431
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/10887
dc.language.isoEnglish
dc.publisherBMC
dc.subjectGUT MICROBIOTA
dc.subjectIMPACT
dc.titleAntibiotic associated diarrhea in outpatient pediatric antibiotic therapy
dc.typeArticle

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