Sublobar resections in early-stage non-small cell lung cancer
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Date
2019
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Abstract
Background: This study aims to evaluate the outcomes ofsublobar resections in patients with early-stage non-small celllung cancer and to investigate the factors affecting survival.Methods: Medical files of a total of 63 patients (52 males,11 females; mean age 64 years; range, 39 to 81 years) whounderwent sublobar resection for suspected or known early-stagenon-small cell lung cancer between January 2001 and August2013 were retrospectively reviewed. Data including demographiccharacteristics of the patients, comorbid conditions, smokingstatus, surgical margin, visceral pleura invasion, distance fromsurgical margin to tumor, tumor size, pathological N status, celltype, tumor localization, and recurrences were recorded.Results: Survival was significantly longer in the patients withnegative surgical margin for tumor (R0) than in those withpositive margin (R1) (94.1 months vs. 32.2 months, p<0.01).Survival was also significantly longer in the patients withoutlymphatic invasion (p<0.01).Conclusion: In early-stage lung tumors, sublobar resection canbe performed, if complete resection is performed. Lymphaticinvasion is a negative prognostic factor for survival followingsublobar resection.