Comparison of Colonoscopy and Histopathological Findings in Terminal Ileum Lesions
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Date
2024
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Abstract Objective In diseases affecting the terminal ileum, the gold standard approach is to image the terminal ileum using colonoscopy and take a biopsy sample. This study aimed to compare the colonoscopic appearance and histopathological findings of the terminal ileum from a diagnostic perspective. Materials and Methods Data were retrospectively collected by screening the files of 971 patients who underwent colonoscopy at the gastroenterology clinic of Celal Bayar University Faculty of Medicine between January 2014 and July 2023. The patients’ demographic data, such as age and gender, were recorded. Colonoscopy reports and histopathological findings were evaluated. Results Of the patients, 457 (47%) were women, and 514 (53%) were men. The mean age was 47.7 years. The number of patients with a normal terminal ileum, both colonoscopically and histopathologically, was 562 (57.8%). The most common finding in the terminal ileum, both colonoscopically and histopathologically, was edematous mucosa 6.1%. The rate of histopathological ileitis detection in patients with a normal terminal ileum on colonoscopy was 4% (27), and the rate of the pathological detection of chronic inflammatory bowel disease in those with an ileal ulcer was 49.1% (28). Conclusion The results of this study showed that the colonoscopic appearance and histopathological findings of terminal ileum lesions were significantly correlated; therefore, both are equally valuable in the diagnosis of ileal diseases. Additionally, ileum intubation and histopathological evaluation must be performed when clinically necessary.