Impairment of EQ-5D-5L Domains According to Allergic Rhinitis and Asthma Control: A MASK-air Real-World Study

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dc.contributor.authorSousa-Pinto, B
dc.contributor.authorLouis, G
dc.contributor.authorRodrigues, J
dc.contributor.authorGiuliano, AFM
dc.contributor.authorBaiardini, I
dc.contributor.authorBraido, F
dc.contributor.authorCzarlewski, W
dc.contributor.authorBedbrook, A
dc.contributor.authorHaahtela, T
dc.contributor.authorValiulis, A
dc.contributor.authorBrussino, L
dc.contributor.authorCecchi, L
dc.contributor.authorCruz, AA
dc.contributor.authorGemicioglu, B
dc.contributor.authorFokkens, WJ
dc.contributor.authorIvancevich, JC
dc.contributor.authorKlimek, L
dc.contributor.authorKraxner, H
dc.contributor.authorKuna, P
dc.contributor.authorKupczyk, M
dc.contributor.authorKvedariene, V
dc.contributor.authorLarenas-Linnemann, D
dc.contributor.authorLouis, R
dc.contributor.authorNadif, R
dc.contributor.authorNiedoszytko, M
dc.contributor.authorOkamoto, Y
dc.contributor.authorOllert, M
dc.contributor.authorPapadopoulos, NG
dc.contributor.authorPatella, V
dc.contributor.authorPawankar, R
dc.contributor.authorPham-Thi, N
dc.contributor.authorPfaar, O
dc.contributor.authorRegateiro, FS
dc.contributor.authorRoche, N
dc.contributor.authorRouadi, PW
dc.contributor.authorSamolinski, B
dc.contributor.authorSastre, J
dc.contributor.authorSavouré, M
dc.contributor.authorScichilone, N
dc.contributor.authorSheikh, A
dc.contributor.authorTaborda-Barata, L
dc.contributor.authorToppila-Salmi, S
dc.contributor.authorYorgancioglu, A
dc.contributor.authorZidarn, M
dc.contributor.authorAnto, JM
dc.contributor.authorZuberbier, T
dc.contributor.authorCanonica, GW
dc.contributor.authorVentura, MT
dc.contributor.authorFonseca, JA
dc.contributor.authorPétré, B
dc.contributor.authorBousquet, J
dc.date.accessioned2024-07-18T12:08:55Z
dc.date.available2024-07-18T12:08:55Z
dc.description.abstractBACKGROUND: EQ-5D-5L (EuroQOL, 5 Domains, 5 Levels) is a widely used health-related quality-of-life instrument, comprising 5 domains. However, it is not known how each domain is impacted by rhinitis or asthma control. OBJECTIVE: To assess the association between rhinitis or asthma control and the different EQ-5D-5L domains using data from the MASK-air mHealth app. METHODS: In this cross-sectional study, we assessed data from all MASK-air users (2015-2021; 24 countries). For the levels of each EQ-5D-5L domain, we assessed rhinitis and asthma visual analog scales (VASs) and the combined symptom-medication score (CSMS). We built ordinal multivariable models assessing the adjusted association between VAS/CSMS values and the levels of each EQ-5D-5L domain. Finally, we compared EQ-5D-5L data from users with rhinitis and self-reported asthma with data from users with rhinitis alone. RESULTS: We assessed 5354 days from 3092 users. We observed an association between worse control of rhinitis or asthma (higher VASs and CSMS) and worse EQ-5D-5L levels. In multivariable models, all VASs and the CSMS were associated with higher levels of pain/discomfort and daily activities. For anxiety/depression, the association was mostly observed for rhinitis-related tools (VAS nose, VAS global, and CSMS), although the presence of self-reported asthma was also associated with worse anxiety/depression. Worse mobility (walking around) was particularly associated with VAS asthma and with the presence of asthma.CONCLUSIONS: A worse rhinitis control and a worse asthma control are associated with higher EQ-5D-5L levels, particularly regarding pain/discomfort and activity impairment. Worse rhinitis control is associated with worse anxiety/depression, and poor asthma control with worse mobility. (c) 2023 American Academy of Allergy, Asthma & Immunology (J Allergy Clin Immunol Pract 2023;11:3742-51)
dc.identifier.issn2213-2198
dc.identifier.other2213-2201
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/11092
dc.language.isoEnglish
dc.publisherELSEVIER
dc.subjectQUALITY-OF-LIFE
dc.subjectHEALTH-STATUS
dc.subjectUTILITY
dc.subjectVALUES
dc.titleImpairment of EQ-5D-5L Domains According to Allergic Rhinitis and Asthma Control: A MASK-air Real-World Study
dc.typeArticle

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