Baseline characteristics of outpatients with heart failure according to phenotype: preliminary analysis from SMYRNA-HF registry

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dc.contributor.authorBihter Şentürk
dc.contributor.authorAhmet Çelik
dc.contributor.authorLütfü Bekar
dc.contributor.authorUmut Uyan
dc.contributor.authorSelcenyakar TÜLÜCE
dc.contributor.authorHakan Güneş
dc.contributor.authorMurat Kerkütlüoğlu
dc.contributor.authorAli Çoner
dc.contributor.authorBarış Kılıçaslan
dc.contributor.authorNurullah Çetin
dc.contributor.authorAyşe Çolak
dc.contributor.authorBurak Açar
dc.contributor.authorİlker Gül
dc.contributor.authorCihan Altın
dc.contributor.authorYalçın Özkurt
dc.contributor.authorMakbule Kutlu Karadağ
dc.contributor.authorEzgi Kalaycıoğlu
dc.contributor.authorMesut Özkahya
dc.contributor.authorTuba Ekin
dc.contributor.authorNuryil YİLMAZ
dc.contributor.authorMehmet Birhan Yılmaz
dc.date.accessioned2024-07-24T09:12:48Z
dc.date.available2024-07-24T09:12:48Z
dc.date.issued2022
dc.description.abstractObjectives: SMYRNA-HF study is a prospective multicenter registry study to determine the profiles of patients with heart failure (HF) in Turkey. This study aimed to present the baseline characteristics of preliminary cohort by comparing them according to different HF phenotypes. Methods: The first SMYRNA-HF cohort included outpatients with HF from 9 centers. Patients were classified into three HF phenotypes as HF with reduced ejection fraction (HFrEF), mildly reduced EF (HFmrEF), and preserved EF (HFpEF) as recommended by guidelines. Results: Overall, 298 patients were included in this preliminary analysis that 57% of the patients were classified as having HFrEF, 33.3% as having HFpEF, and 9.7% as having HFmrEF. Female gender was more common in HFpEF (p = 0.003). Age, frequency of diabetes mellitus, use of angiotensin-converting enzyme inhibitors/angiotensin receptor blocker, use of beta-blocker, use of daily loop diuretic, heart rate, blood urea nitrogen levels, lipid profiles, hemoglobin, white blood cell, platelet levels were similar among three HF phenotypes. Body mass index (BMI) (p < 0.001), frequency of hypertension (HT) (p < 0.001), and atrial fibrillation (AF) (p = 0.015) were higher in HFpEF. Ischemic etiology (p < 0.001) was less frequent in HFpEF. Use of mineralocorticoid receptor antagonist was higher in HFrEF (p < 0.001). Conclusions: Our study presented the baseline characteristics of outpatients with HF in Turkey. There were significant differences among HF phenotypes in terms of gender, BMI, frequency of HT, AF, and ischemic etiology. Treatment implementations seem to follow the guidelines. Although the rates are low, new treatment approaches recommended in the most recent guidelines seem to enter clinical practice.
dc.identifier.DOI-ID10.18621/eurj.1049360
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/24794
dc.language.isoeng
dc.titleBaseline characteristics of outpatients with heart failure according to phenotype: preliminary analysis from SMYRNA-HF registry
dc.typeAraştırma Makalesi

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