ANTIMICROBIAL AND SOD-LIKE ACTIVITIES OF N,N'-BIS(FERROCENYLMETHYLENE)ETHYLENEDIAMINE SCHIFF BASE AND IT'S METAL COMPLEXES

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dc.contributor.authorÖzbek, HA
dc.contributor.authorÇinar, S
dc.contributor.authorOskay, M
dc.contributor.authorAydemir, T
dc.contributor.authorDemirhan, F
dc.date.accessioned2024-07-18T11:51:52Z
dc.date.available2024-07-18T11:51:52Z
dc.description.abstractThe synthesized N,N'-bis(ferrocenylmethylene)ethylenediamine Schiff base and it's metal complexes were screened in vitro for antimicrobial activity against two Gram-positive (Staphylococcus aureus ATCC 25923, Bacillus cereus ATCC 7064), four Gram-negative (Escherichia coli ATCC 25922, Citrobacter koseri DBCC 01, Entorebacter aeruginosa ATCC 13048, Salmonella typhimurium DBCC 02) and antifungal activity against a Candida albicans. MIC values of the compounds ranged from 27 to 533 mu g/mL. Compound (5) showed very strong activity against S. aureus with the best MIC (27 mu g/mL). The lowest MIC for C. albicans was obtained 107 mu g/mL. The superoxide dismutase activity of Schiff base and it's metal complexes has been measured and discussed. SOD-like activities of bis ferrocenyl Schiff base ligand metal complexes were investigated using NBT. While only the Cu (II) complex showed SOD-like (40 mu m IC50) activity, the SOD-like activity value was not determined in the other complex and ligand.
dc.identifier.issn0717-9707
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/5176
dc.language.isoEnglish
dc.publisherSOC CHILENA QUIMICA
dc.subjectBENZIMIDAZOLIUM IODIDE SALTS
dc.subjectIN-VITRO ACTIVITY
dc.subjectSUPEROXIDE-DISMUTASE
dc.subjectN-FERROCENYLMETHYL
dc.subjectCRYSTAL-STRUCTURE
dc.subjectFERROCENE
dc.subjectLIGAND
dc.subjectCU(II)
dc.subjectELECTROCHEMISTRY
dc.subjectANTIOXIDANT
dc.titleANTIMICROBIAL AND SOD-LIKE ACTIVITIES OF N,N'-BIS(FERROCENYLMETHYLENE)ETHYLENEDIAMINE SCHIFF BASE AND IT'S METAL COMPLEXES
dc.typeArticle

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