HALP Score as a New Prognostic Index in Metastatic Renal Cell Cancer
| dc.contributor.author | Ekinci F. | |
| dc.contributor.author | Balcik O.Y. | |
| dc.contributor.author | Oktay E. | |
| dc.contributor.author | Erdogan A.P. | |
| dc.date.accessioned | 2025-04-10T11:04:43Z | |
| dc.date.available | 2025-04-10T11:04:43Z | |
| dc.date.issued | 2022 | |
| dc.description.abstract | Objective: To evaluate prognostic significance of the new index, designed by formulating hemoglobin, albumin, lymphocyte, and platelet (HALP) counts in patients with metastatic renal cell carcinoma (RCC). Study Design: Descriptive study. Place and Duration of Study: Department of Medical Oncology, Celal Bayar University, Manisa, Turkey and Adnan Menderes University, Aydin, Turkey, from January 2014 to April 2020. Methodology: Patients with metastatic RCC and sufficient follow-up data were included in the study as a retrospective cohort. HALP score was calculated as hemoglobin (g/L) × albumin (g/L) levels × lymphocyte count (/L)/platelet count (/L). The cut-off value was determined by examining the area under the ROC curve for the HALP value. The endpoints of this study included overall survival (OS) and progression-free survival (PFS). Results: The mean overall survival (OS) of the patients with low HALP score was 17.7 months (95% CI, 2.21 - 33.18), while the OS of the patients with high HALP score was 89.7 months (95% CI, 55.62 - 123.77) and reached statistical significance (p=0.001). The results of univariate (p = 0.009) and multivariate (p=0.012) analyses were statistically significant as well. Conclusion: The HALP score in metastatic RCC patients was closely related to the prognosis. Worse OS was found in patients with a low HALP score. © 2022 College of Physicians and Surgeons Pakistan. All rights reserved. | |
| dc.identifier.DOI-ID | 10.29271/jcpsp.2022.03.313 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.14701/45567 | |
| dc.publisher | College of Physicians and Surgeons Pakistan | |
| dc.title | HALP Score as a New Prognostic Index in Metastatic Renal Cell Cancer | |
| dc.type | Article |