Evaluation of patients with zygomycosis

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dc.contributor.authorBetil BAYSAN ÖZHAK
dc.contributor.authorÇiğdem Banu Çetin
dc.contributor.authorVildan OĞUZ AVKAN
dc.contributor.authorSema ÇAVUŞ ALP
dc.contributor.authorHüsnü PULLUKÇU
dc.contributor.authorDilek Yeşim Metin
dc.contributor.authorMeltem AVCI
dc.contributor.authorMustafa Bülent ERTUĞRUL
dc.contributor.authorNur YAPAR
dc.contributor.authorOzge Turhan
dc.contributor.authorOnur Kaya
dc.contributor.authorMeltem TAŞBAKAN IŞIKGÖZ
dc.contributor.authorŞEBNEM ŞENOL AKAR
dc.contributor.authorSELDA SAYIN KUTLU
dc.contributor.authorGulsen Mermut
dc.date.accessioned2025-04-14T05:50:17Z
dc.date.available2025-04-14T05:50:17Z
dc.date.issued2014
dc.description.abstractAim: Zygomycosis is a severe angioinvasive infection caused by Zygomycetes. We retrospectively investigated 16 cases of zygomycosis. Materials and methods: The data of patients, who had been followed between 2004 and 2010 in 8 tertiary-care teaching hospitals, were reviewed. Demographic characteristics, underlying diseases, and clinical signs and symptoms of the patients, as well as diagnostic methods, data obtained by radiological imaging methods, and the therapies, were recorded. Therapeutic approaches, antifungal agents and duration of use, and the characteristics of the cases were identified. Results: The study included 11 female and 5 male subjects. The most common symptoms and clinical signs were fever (n = 9) and retroorbital pain (n = 7). Rhinocerebral zygomycosis was the most common form. The mean time elapsed for diagnosis was 14.26 ± 13.96 (range: 2 52) days. Antifungal therapy was given to 15 patients (94%). In addition to antifungal therapy, 12 patients underwent surgical intervention 1 to 4 times. The mean duration of receiving antifungal therapy was 61.4 ± 58.02 (range: 1 180) days. The median duration of treatment was 62.5 (range: 42 180) days in survivors. Conclusion: Zygomycosis is an infectious disease with high mortality despite antifungal therapy and surgical interventions.
dc.identifier.urihttp://hdl.handle.net/20.500.14701/53764
dc.language.isoİngilizce
dc.subjectTıbbi Araştırmalar Deneysel
dc.subjectGenel ve Dahili Tıp
dc.subjectEnfeksiyon Hastalıkları
dc.titleEvaluation of patients with zygomycosis

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