The Effect of an Eight-Week Walking Program on Bone Turnover Markers and sRANKL/Osteoprotegerin Levels in Post-Menopausal Women
| dc.contributor.author | Büyükyazi, G | |
| dc.date.accessioned | 2024-07-18T11:40:25Z | |
| dc.date.available | 2024-07-18T11:40:25Z | |
| dc.description.abstract | Objective: To examine the effect of an eight-week moderate intensity walking program on bone turnover markers, serum osteoprotegerin (OPG) and soluble receptor-activator of nuclear factor- kappa beta ligand (sRANKL) in post-menopausal women. Material and Methods: Twelve post-menopausal women (45-62 years) completed an eight-week walking program at moderate intensity (60-65% maximum heart rate reserve). Non-walking women served as the control group (CG; n= 11). Body weight, percent body fat, body mass index (BMI), estimated maximal oxygen consumption (estimated VO2(max)), bone turnover markers, sRANKL, serum OPG and sRANKL/OPG ratio were measured before and after the intervention. Results: Eight-week walking program produced significant increases in VO2(max) and reductions in body weight and BMI. Serum intact parathyroid hormone (iPTH), and beta- crosslaps (CTx) reduced (p< 0.01, for both), sRANKL/OPG ratio (p< 0.01) and sRANKL values (p< 0.05) increased in the exercise group (EG). We detected significant reductions in the serum OPG levels of EG and CG (p< 0.01). No significant differences were observed between the changes in EG and CG in terms of bone turnover markers, OPG and sRANKL values. Conclusion: Eight-week moderate intensity walking program is beneficial for improving cardiorespiratory function in post-menopausal women to enable them to lead a less risky and a more independent life; however, it seems not so effective in changing the bone turnover markers and the OPG/sRANKL system. | |
| dc.identifier.issn | 1300-0292 | |
| dc.identifier.other | 2146-9040 | |
| dc.identifier.uri | http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/2382 | |
| dc.language.iso | English | |
| dc.publisher | ORTADOGU AD PRES & PUBL CO | |
| dc.subject | MINERAL DENSITY | |
| dc.subject | QUANTITATIVE ULTRASOUND | |
| dc.subject | WEIGHT-BEARING | |
| dc.subject | BRISK WALKING | |
| dc.subject | OSTEOPROTEGERIN | |
| dc.subject | EXERCISE | |
| dc.subject | SERUM | |
| dc.subject | METABOLISM | |
| dc.subject | DISEASE | |
| dc.subject | OVERWEIGHT | |
| dc.title | The Effect of an Eight-Week Walking Program on Bone Turnover Markers and sRANKL/Osteoprotegerin Levels in Post-Menopausal Women | |
| dc.type | Article |