What We Learned about COVID-19 So Far? Notes from Underground

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dc.contributor.authorFatma TOKGÖZ AKYIL
dc.contributor.authorDilek KARADOĞAN
dc.contributor.authorCanan GÜNDÜZ
dc.contributor.authorAycan YÜKSEL
dc.contributor.authorHüseyin ARIKAN
dc.contributor.authorTuğba ŞİŞMANLAR EYÜBOĞLU
dc.contributor.authorNagehan EMİRALİOĞLU
dc.contributor.authorTuğba RAMASLI GÜRSOY
dc.contributor.authorİrem ŞERİFOĞLU
dc.contributor.authorZehra Nur TÖREYİN
dc.contributor.authorFeride MARİM
dc.contributor.authorBilge YILMAZ KARA
dc.contributor.authorHilal ÖZAKINCI
dc.contributor.authorElif DEVELİ
dc.contributor.authorSelin ÇAKMAKÇI
dc.contributor.authorTuba ÇİFTÇİ KÜSBECİ
dc.contributor.authorOğuz KARCIOĞLU
dc.contributor.authorPınar Yıldız GÜLHAN
dc.contributor.authorMerve ERÇELİK
dc.contributor.authorBerrin ER
dc.contributor.authorÖzlem ATAOĞLU
dc.contributor.authorDemet POLAT
dc.contributor.authorİlknur KAYA
dc.contributor.authorTuğba Aslı ÖNYILMAZ
dc.contributor.authorAsena AYDIN
dc.contributor.authorDeniz KIZILIRMAK
dc.contributor.authorAslıhan Banu ER
dc.contributor.authorMukaddes KILINÇ
dc.contributor.authorFatma Esra GÜNAYDIN
dc.contributor.authorSelçuk GÜRZ
dc.contributor.authorSelen KARAOĞLANOĞLU
dc.contributor.authorSelma ÇELİK
dc.contributor.authorDorina ESENDAĞLI
dc.contributor.authorHüseyin TOPTAY
dc.contributor.authorÜmran Özden SERTÇELİK
dc.contributor.authorMetin AKGÜN
dc.date.accessioned2024-07-24T09:12:24Z
dc.date.available2024-07-24T09:12:24Z
dc.date.issued2020
dc.description.abstractThe novel coronavirus pandemic poses a major global threat to public health. Our knowledge concerning every aspect of COVID-19is evolving rapidly, given the increasing data from all over the world. In this narrative review, the Turkish Thoracic Society Early CareerTaskforce members aimed to provide a summary on recent literature regarding epidemiology, clinical findings, diagnosis, treatment,prevention, and control of COVID-19. Studies revealed that the genetic sequence of the novel coronavirus showed significant identityto SARS-CoV and MERS-CoV. Angiotensin-converting enzyme 2 receptor is an important target of the SARS-CoV-2 while entering anorganism. Smokers were more likely to develop the disease and have a higher risk for ICU admission. The mean incubation periodwas 6.4 days, whereas asymptomatic transmission was reported up to 25 days after infection. Fever and cough were the most commonsymptoms, and cardiovascular diseases and hypertension were reported to be the most common comorbidities among patients. Clinicalmanifestations range from asymptomatic and mild disease to severe acute respiratory distress syndrome. Several patients showed typicalsymptoms and radiological changes with negative RT-PCR but positive IgG and IgM antibodies. Although radiological findings may vary,bilateral, peripherally distributed, ground-glass opacities were typical of COVID-19. Poor prognosis was associated with older age, higherSequential Organ Failure Assessment score, and high D-dimer level. Chloroquine was found to be effective in reducing viral replicationin vitro. Likewise, protease inhibitors, including lopinavir/ritonavir, favipiravir, and nucleoside analogue remdesivir were proposed to bethe potential drug candidates in COVID-19 management. Despite these efforts, we still have much to learn regarding the transmission,treatment, and prevention of COVID-19
dc.identifier.DOI-ID10.5152/TurkThoracJ.2020.20052
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/24478
dc.language.isoeng
dc.titleWhat We Learned about COVID-19 So Far? Notes from Underground
dc.typeDerleme

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