Synthesis and antimicrobial activities of two novel amino sugars derived from chloraloses

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dc.contributor.authorYenil N.
dc.contributor.authorAy E.
dc.contributor.authorAy K.
dc.contributor.authorOskay M.
dc.contributor.authorMaddaluno J.
dc.date.accessioned2024-07-22T08:20:51Z
dc.date.available2024-07-22T08:20:51Z
dc.date.issued2010
dc.description.abstractThe synthesis of 5-amino-5-deoxy-1,2-O-(S)-trichloroethylidene-β-l-arabinofuranose and 6-amino-6-deoxy-1,2-O-(S)-trichloroethylidene-α-d-glucofuranose is described by a simple three- or four-step route. Antibacterial potency of the new compounds was determined using an inhibition zone diameter test. The results show that these compounds have a broad-spectrum activity against Gram-positive, Gram-negative bacteria and Candida albicans. © 2010 Elsevier Ltd. All rights reserved.
dc.identifier.DOI-ID10.1016/j.carres.2010.03.043
dc.identifier.issn00086215
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18355
dc.language.isoEnglish
dc.subjectAmino Sugars
dc.subjectAnti-Infective Agents
dc.subjectBacteria
dc.subjectChloralose
dc.subjectFungi
dc.subjectMicrobial Sensitivity Tests
dc.subjectStereoisomerism
dc.subjectCandida albicans
dc.subjectNegibacteria
dc.subjectPosibacteria
dc.subjectAmines
dc.subjectBacteria
dc.subjectSugar (sucrose)
dc.subject1,2 o trichloroethylidene beta levo arabinofuranose
dc.subject3,5 di o acetyl trichloroethylidene beta levo arabinofuranose
dc.subject5 acetamido 5 deoxy 3 o acetyl 1,2 o trichloroethylidene beta levo arabinofuranose
dc.subject5 amino 5 deoxy 1,2 o trichloroethylidene beta levo arabinofuranose
dc.subject5 azido 5 deoxy 1,2 o trichloroethylidene beta levo arabinofuranose
dc.subject5 o tosyl 1,2 o trichloroethylidene beta levo arabinofuranose
dc.subject6 acetamido 6 deoxy 3,5 di o acetyl 1,2 o trichloroethylidene alpha dextro glucofuranose
dc.subject6 amino 6 deoxy 1,2 o trichloroethylidene alpha dextro glucofuranose
dc.subject6 azido 6 deoxy 1,2 o trichloroethylidene alpha dextro glucofuranose
dc.subject6 o tosyl 1,2 o trichloroethylidene alpha dextro glucofuranose
dc.subjectaminosugar
dc.subjectantibiotic agent
dc.subjectcarbohydrate derivative
dc.subjectchloralose
dc.subjectchloramphenicol
dc.subjectnalidixic acid
dc.subjectnystatin
dc.subjectunclassified drug
dc.subjectaminosugar
dc.subjectantiinfective agent
dc.subjectAmino sugar
dc.subjectAnti-microbial activity
dc.subjectCandida albicans
dc.subjectGram-negative bacteria
dc.subjectInhibition zones
dc.subjectantibacterial activity
dc.subjectarticle
dc.subjectBacillus cereus
dc.subjectBacillus subtilis
dc.subjectCandida albicans
dc.subjectcarbohydrate synthesis
dc.subjectcompetitive inhibition
dc.subjectcontrolled study
dc.subjectdrug potency
dc.subjectdrug structure
dc.subjectdrug synthesis
dc.subjectEnterobacter aerogenes
dc.subjectEnterobacter cloacae
dc.subjectEnterococcus faecalis
dc.subjectEscherichia coli
dc.subjectminimum inhibitory concentration
dc.subjectnonhuman
dc.subjectpriority journal
dc.subjectProteus vulgaris
dc.subjectSalmonella typhimurium
dc.subjectStaphylococcus aureus
dc.subjectanalogs and derivatives
dc.subjectBacteria
dc.subjectchemistry
dc.subjectdrug effects
dc.subjectfungus
dc.subjectmicrobial sensitivity test
dc.subjectstereoisomerism
dc.subjectsynthesis
dc.subjectComplexation
dc.titleSynthesis and antimicrobial activities of two novel amino sugars derived from chloraloses
dc.typeArticle

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