Effects of eccentric exercise-induced delayed onset muscle soreness on endoplasmic reticulum stress-related markers
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Date
2021
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Abstract
Short Communications: Apelin, pentraxin3 (PTX3), and
interleukin6 (IL6) parameters are known as inflammation
markers and found to be related to endoplasmic reticulum
(ER) stress. The aimof the studywas to investigate the effect
of eccentric exercise-induced delayed onset muscle soreness
(DOMS) on ER stress-related markers in young athletes.
Objectives and Methods: ER stress and DOMS-related
blood markers, maximal strength level, and rate of perceived
exertion using the visual analog scale (VAS) were
assessed before, immediately after, 24, 48, and 72 h after
the muscle damage protocol. Results: IL6 peaked 24 h after while creatine kinase and
lactate dehydrogenase enzyme levels reached their peaks
at 72 h after the protocol. The level of apelin continued to
increase throughout the four measurements, and PTX3
peaked at 24 h, and then declined to the levels before the
protocol but the differences were not significant. The significant
decrease in the strength and the significant increase
in VAS continued 48 h after the protocol.
Conclusion: ER is activated and ER stress occurred, due to
increases in IL6, PTX3 and apelin levels after the test protocol
concluded that a single vigorous eccentric exercise
should be avoided in harmful effect on health as parallel
with Physical Activity Guidelines.