Clinical characteristics of patients requiring lung transplantation referral in national cystic fibrosis registry data

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dc.contributor.authorAyşen Bingöl
dc.contributor.authorERDEM BAŞARAN
dc.contributor.authorGökçen Dilşa Tuğcu
dc.contributor.authorSanem Eryilmaz Polat
dc.contributor.authorAbdulhamit Çollak
dc.contributor.authorSelcuk Uzuner
dc.contributor.authorNihat Sapan
dc.contributor.authorZeynep Reyhan Onay
dc.contributor.authorTugba Ramasli Gursoy
dc.contributor.authorNural Kiper
dc.contributor.authorNagehan Emiralioglu
dc.contributor.authorHaluk Cezmi cokugras
dc.contributor.authorSebnem Ozdogan
dc.contributor.authorPervin Korkmaz
dc.contributor.authorSukru Cekic
dc.contributor.authorZEYNEP ÜLKER TAMAY
dc.contributor.authorAzer Kilic Baskan
dc.contributor.authorMehmet Alp Kose
dc.contributor.authorEbru Damadoglu
dc.contributor.authorTugba Sismanlar Eyuboglu
dc.contributor.authorAyse Tana Aslan
dc.contributor.authorGonca KILIÇ
dc.contributor.authorNAZAN ÇOBANOGLU
dc.contributor.authorSEVGI PEKCAN
dc.contributor.authorUĞUR ÖZÇELİK
dc.contributor.authorDeniz Dogru
dc.contributor.authorGUZIN CINEL
dc.contributor.authorEbru Yalcin
dc.contributor.authorHadice Selimoğlu Şen
dc.contributor.authorvelat ŞEN
dc.contributor.authorGökçen ünal
dc.contributor.authorAsli imran YILMAZ
dc.contributor.authorAyse Ayzit Kilinc
dc.contributor.authorHakan Yazan
dc.contributor.authorAyse Senay Sasihuseyinoglu
dc.contributor.authorDilek ÖZCAN
dc.contributor.authorDerya Ufuk Altintas
dc.contributor.authorGökçen Kartal Öztürk
dc.contributor.authorEsen Demir
dc.contributor.authorIlim Irmak
dc.contributor.authorAli Özdemir
dc.contributor.authorkoray harmancı
dc.contributor.authorMelih Hangul
dc.contributor.authorHasan Yuksel
dc.contributor.authorGizem ÖZCAN
dc.contributor.authorerdem topal
dc.contributor.authorDemet Can
dc.contributor.authorGönül Çaltepe
dc.contributor.authorMehmet KILIÇ
dc.contributor.authorErkan CAKIR
dc.date.accessioned2025-04-14T05:52:20Z
dc.date.available2025-04-14T05:52:20Z
dc.date.issued2023
dc.description.abstractBackground. We aimed to determine the number of cystic fibrosis (CF) patients recorded in the Cystic Fibrosis Registry of Türkiye (CFRT) who were in need of lung transplantation (LT) referral and examine clinical differences between patients who were LT candidates due to rapid forced expiratory volume in one second (FEV₁) decline and LT candidates without rapid FEV₁ decline in the last year to identify a preventable cause in patients with such rapid FEV₁ decline. Methods. All CF patients recorded in the CFRT in 2018 were evaluated in terms of LT. Patients were divided into those with FEV₁ below 50% and in need of LT due to a decrease of 20% or more in the previous year (Group 1) and those who did not have FEV₁ decline of more than 20% in the previous year but had other indications for LT (Group 2). Demographic and clinical features were compared between the two groups. Results. Of 1488 patients registered in CFRT, 58 had a need for LT. Twenty patients were included in Group 1 and others in Group 2. Our findings did not reveal any significant variations in treatment, chronic infection status, or complications between the two groups. The average weight z-score was significantly higher in Group 1. Positive correlations were detected between weight z-score and FEV₁ in 2017 in Group 1 and between FEV₁ values in 2017 and 2018 in Group 2. Conclusions. There appears to be a relationship between the nutritional status and weight z-scores of CF patients and pulmonary function, which may indirectly affect the need for lung transplantation referral.
dc.identifier.DOI-ID10.24953/turkjped.2021.4930
dc.identifier.urihttp://hdl.handle.net/20.500.14701/55259
dc.language.isoİngilizce
dc.subjectSolunum Sistemi
dc.subjectTransplantasyon
dc.titleClinical characteristics of patients requiring lung transplantation referral in national cystic fibrosis registry data

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