Radiologic and Clinical Characteristics of Rheumatoid Arthritis-associated Lung Disease
| dc.contributor.author | Arman Gazi | |
| dc.contributor.author | Özgül SOYSAL GÜNDÜZ | |
| dc.date.accessioned | 2024-07-24T09:07:43Z | |
| dc.date.available | 2024-07-24T09:07:43Z | |
| dc.date.issued | 2022 | |
| dc.description.abstract | Objective: Rheumatoid arthritis (RA) is a chronic inflammatory disease that usu ally affects the synovial joints, but can also affect other organs. One of the most common forms of extra-articular manifestations is RA-associated lung disease (RA LD), which causes significant morbidity and mortality. There are several pulmonary findings of RA, including pulmonary parenchymal disease, pleural inflammation, airway diseases, vasculitis, and pulmonary hypertension. It has been reported that the most common pulmonary disease is interstitial lung disease in RA patients. The aim of this study is assessing the tomographic findings of RA-LD patients of a single center, and their possible correlation with the clinical and laboratory findings of the disease. Material and Methods: Medical records of 32 RA-LD patients were investigated ret rospectively. The radiological, clinical, and laboratory data, disease activity and dis ability scores were recorded. Results: 32 patients (78% female) with a mean age of 50.23±10.48 years were in cluded in the study. The mean disease duration was 52.42±15.48 months. Pulmonary lesions were detected on chest X-ray in 16 patients (50%) and on high resolution computed tomography (HRCT) scans in all of 32 patients. Parenchymal involvement was detected in 25 patients (78.1%). The most common lesions seen on HRCT scans were pulmonary nodules (31.2%), ground-glass attenuation (25%), and bronchiecta sis (25%). No association was found between radiological involvement patterns and laboratory findings, DAS28-CRP, and medications (p>0.05 for all). Conclusion: In the presence of a pulmonary lesion on X-ray, HRCT should be con sidered in every RA patients. Parenchymal involvement is the most common pattern in RA-LD. In addition, pulmonary nodules may be seen frequently in young and female RA patients. | |
| dc.identifier.DOI-ID | 10.14744/IGH.2022.92486 | |
| dc.identifier.issn | 1300-4115 | |
| dc.identifier.uri | http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/20754 | |
| dc.language.iso | eng | |
| dc.title | Radiologic and Clinical Characteristics of Rheumatoid Arthritis-associated Lung Disease | |
| dc.type | Araştırma Makalesi |