Cutaneous leishmaniasis infection in Balb/c mice using a Leishmania tropica strain isolated from Turkey

Simple item page
dc.contributor.authorGirginkardesler, N
dc.contributor.authorBalcioglu, IC
dc.contributor.authorYereli, K
dc.contributor.authorÖzbilgin, A
dc.contributor.authorÖzbel, Y
dc.date.accessioned2024-07-18T12:00:35Z
dc.date.available2024-07-18T12:00:35Z
dc.description.abstractLeishmania tropica, which is endemic in Turkey, is the causative agent of cutaneous leishmaniasis. Leishmania tropica promastigotes (2 x 10(7)) isolated from a patient with dermal leishmaniasis and reproduced in NNN medium were inoculated subcutaneously into the footpads of 10 Balb/c mice. Cutaneous leishmaniasis developed on the footpads of 4 mice approximately 45 days later. Leishmania tropica amastigotes were observed in smear slides and then cultivated in NNN medium. Balb/c mice are a suitable laboratory model for this isolate of L. tropica and thus a source of amastigotes for studies on the immunology, chemotherapy, and pathogenicity of cutaneous leishmaniasis.
dc.identifier.issn0022-3395
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/7813
dc.language.isoEnglish
dc.publisherAMER SOC PARASITOLOGISTS
dc.titleCutaneous leishmaniasis infection in Balb/c mice using a Leishmania tropica strain isolated from Turkey
dc.typeArticle

Files

Collections

Web of Science Koleksiyonu