Does a patient-specific bladder-filling protocol affect bladder volume and dose in postprostatectomy radiotherapy?

dc.contributor.authorYalman, D
dc.contributor.authorKöylü, M
dc.contributor.authorDuran, O
dc.date.accessioned2024-07-18T11:53:22Z
dc.date.available2024-07-18T11:53:22Z
dc.description.abstractPurposeOur aim is to develop a patient-specific bladder-filling protocol (PSP) using an ultrasound-based bladder scanner (BS) and compare the volumetric and dosimetric parameters with those of the standard filling protocol (SP) in postprostatectomy patients.MethodsTwenty postprostatectomy patients who received salvage radiotherapy (72 Gy/36 fx) were included. For PSP, the patient was asked to drink 500 mL of water after emptying his bladder. Bladder volume was measured using BS every 10 min. Each patient's unique time to reach a 150-200 cc volume was used for simulation and treatment. For the SP, the patient was asked about the feeling of having a full bladder. Organs at risk (OAR) were contoured on cone-beam computed tomography (CBCT) scans that were transferred to the treatment planning system (TPS). Treatment plans were applied to CBCTs. Changes in bladder volume and doses for planning computed tomography (PCT) and CBCT were determined.ResultsIn the SP, there was no significant difference in mean bladder volume for PCT and CBCT (p = 0.139); however, there was a trend for significance in the mean bladder dose (p = 0.074). In PSP, there was no significant difference in the mean bladder volume or dose for PCT and CBCT (p = 0.139 and p = 0.799, respectively). There was a significant difference in terms of mean CBCT bladder volume between the two protocols (p = 0.007), whereas no significant difference was detected in terms of bladder dose (p = 0.130).ConclusionWith PSP, optimal bladder filling was obtained and maintained throughout the whole treatment course, and it was reproducible in every fraction.
dc.identifier.issn0301-1623
dc.identifier.other1573-2584
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/5559
dc.language.isoEnglish
dc.publisherSPRINGER
dc.subjectBEAM-COMPUTED-TOMOGRAPHY
dc.subjectCONFORMAL RADIOTHERAPY
dc.subjectRADIATION-THERAPY
dc.subjectTARGET VOLUME
dc.subjectPROSTATE
dc.subjectCANCER
dc.subjectRECTUM
dc.subjectVARIABILITY
dc.subjectCONSISTENCY
dc.subjectPOSITION
dc.titleDoes a patient-specific bladder-filling protocol affect bladder volume and dose in postprostatectomy radiotherapy?
dc.typeArticle

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