Clinical characteristics of patients requiring lung transplantation referral in national cystic fibrosis registry data

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dc.contributor.authorZeynep Reyhan ONAY
dc.contributor.authorTuğba ŞİŞMANLAR EYÜBOĞLU
dc.contributor.authorAyşe TANA ASLAN
dc.contributor.authorTuğba RAMASLI GÜRSOY
dc.contributor.authorEbru Yalcin
dc.contributor.authorNural KİPER
dc.contributor.authorNagehan EMİRALİOĞLU
dc.contributor.authorHadice SELİMOĞLU ŞEN
dc.contributor.authorVelat ŞEN
dc.contributor.authorGökçen ÜNAL
dc.contributor.authorAslı TÜRKUT YILMAZ
dc.contributor.authorAyse AYZİT KİLİNC
dc.contributor.authorHaluk ÇOKUĞRAŞ
dc.contributor.authorAzer Kilic Baskan
dc.contributor.authorHakan YAZAN
dc.contributor.authorAbdulhamit ÇOLLAK
dc.contributor.authorSelçuk UZUNER
dc.contributor.authorAyse Senay SASİHUSEYİNOGLU
dc.contributor.authorDilek DOĞRUEL
dc.contributor.authorDerya UFUK ALTINTAŞ
dc.contributor.authorGökçen ÖZTÜRK
dc.contributor.authorEsen DEMİR
dc.contributor.authorAyşen BİNGÖL
dc.contributor.authorErdem BAŞARAN
dc.contributor.authorSukru Cekic
dc.contributor.authorNihat SAPAN
dc.contributor.authorİlim IRMAK
dc.contributor.authorEbru ÇELEBİOĞLU
dc.contributor.authorGökçen Dilşa TUĞCU
dc.contributor.authorSanem ERYILMAZ POLAT
dc.contributor.authorAli OZDEMİR
dc.contributor.authorKoray HARMANCI
dc.contributor.authorMelih HANGÜL
dc.contributor.authorMehmet Alp Kose
dc.contributor.authorZEYNEP ÜLKER TAMAY
dc.contributor.authorHasan Yuksel
dc.contributor.authorGizem ÖZCAN
dc.contributor.authorErdem TOPAL
dc.contributor.authorDemet CAN
dc.contributor.authorPERVİN KORKMAZ EKREN
dc.contributor.authorGönül ÇALTEPE
dc.contributor.authorMehmet KILIÇ
dc.contributor.authorSebnem Ozdogan
dc.contributor.authorErkan CAKIR
dc.contributor.authorNazan ÇOBANOĞLU
dc.contributor.authorSevgi PEKCAN
dc.contributor.authorGüzin CİNEL
dc.contributor.authorUğur ÖZÇELİK
dc.contributor.authorDENİZ DOĞRU ERSÖZ
dc.contributor.authorGonca KILIÇ
dc.date.accessioned2024-07-24T09:14:27Z
dc.date.available2024-07-24T09:14:27Z
dc.date.issued2023
dc.description.abstractBackground. We aimed to determine the number of cystic fibrosis (CF) patients recorded in the Cystic Fibrosis Registry of Türkiye (CFRT) who were in need of lung transplantation (LT) referral and examine clinical differences between patients who were LT candidates due to rapid forced expiratory volume in one second (FEV₁) decline and LT candidates without rapid FEV₁ decline in the last year to identify a preventable cause in patients with such rapid FEV₁ decline. Methods. All CF patients recorded in the CFRT in 2018 were evaluated in terms of LT. Patients were divided into those with FEV₁ below 50% and in need of LT due to a decrease of 20% or more in the previous year (Group 1) and those who did not have FEV₁ decline of more than 20% in the previous year but had other indications for LT (Group 2). Demographic and clinical features were compared between the two groups. Results. Of 1488 patients registered in CFRT, 58 had a need for LT. Twenty patients were included in Group 1 and others in Group 2. Our findings did not reveal any significant variations in treatment, chronic infection status, or complications between the two groups. The average weight z-score was significantly higher in Group 1. Positive correlations were detected between weight z-score and FEV₁ in 2017 in Group 1 and between FEV₁ values in 2017 and 2018 in Group 2. Conclusions. There appears to be a relationship between the nutritional status and weight z-scores of CF patients and pulmonary function, which may indirectly affect the need for lung transplantation referral.
dc.identifier.DOI-ID10.24953/turkjped.2021.4930
dc.identifier.issn0041-4301
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/26086
dc.language.isoeng
dc.titleClinical characteristics of patients requiring lung transplantation referral in national cystic fibrosis registry data
dc.typeAraştırma Makalesi

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