The Results of the 24-Hour Ambulatory Blood Pressure Monitoring of the Essential Hypertension Patients Using Diuretic or Not
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Researchers have discovered that blood pressure (BP) varies in a diurnal manner throughout a 24-hour period, being higher during the day and lower at night. Most people have a dipping BP pattern characterized by a nighttime BP that is 10-20% lower than their daytime BP. First time treated essential hypertensive non-diabetic patients in Hypertension and Nephrology Outpatient Clinic were randomly allocated to two different groups according to their hydrochlorothiazide usage status in addition to other antihypertensive drugs. Age, gender, body mass index (BM)), duration of hypertension and initial fasting blood sugar, total cholesterol, HDL-cholesterol, LDL-cholesterol, uric acid. BUN, creatinine, Na, K, calcium levels were not different betwe en the groups. During their follow-up, the attainment of 140(90 mmHg or less blood pressure levels for three consecutive monthly controls prompted the implementation of 24-hour ambulatory blood pressure monitoring (ABPM). The interval between the first office visit and the last control was also comparable between the groups. At the last clinic visit, the groups were again compared for BMI. and the same biochemical parameters. There was not any statistically significant difference between the subgroups. Twenty-four-hour ABPM results were also comparable. These findings suggest that the same blood pressure target can be achieved in essential hypertensives with the combinalion therapy regardless of die use of hydrochlorothiazide.