Asthma-chronic obstructive pulmonary disease overlap: Results from a national-multicenter study

Simple item page
dc.contributor.authorGülfem Elif ÇELİK
dc.contributor.authorÖmür AYDIN
dc.contributor.authorElif ŞEN
dc.contributor.authorTunçalp DEMİR
dc.contributor.authorBilun GEMİCİOĞLU
dc.contributor.authorEsen KIYAN
dc.contributor.authorDilşad MUNGAN
dc.contributor.authorİpek KIVILCIM OĞUZÜLGEN
dc.contributor.authorMehmet POLATLI
dc.contributor.authorÖzlem GÖKSEL
dc.contributor.authorAbdullah SAYINER
dc.contributor.authorNurhayat YILDIRIM
dc.contributor.authorFüsun YILDIZ
dc.contributor.authorArzu YORGANCIOĞLU
dc.contributor.authorAtilla Halil ELHAN
dc.contributor.authorÖznur YILDIZ
dc.contributor.authorİlknur BAŞYİĞİT
dc.contributor.authorŞermin BÖREKÇİ
dc.contributor.authorYavuz HAVLUCU
dc.contributor.authorGülfer OKUMUŞ
dc.contributor.authorMurat TÜRK
dc.contributor.authorSevgi SARYAL
dc.date.accessioned2024-07-24T09:14:49Z
dc.date.available2024-07-24T09:14:49Z
dc.date.issued2024
dc.description.abstractAsthma-chronic obstructive pulmonary disease overlap: Results from a national-multicenter study Introduction: Patients with asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) have a greater disease burden than those with COPD or asthma alone. In this study, it was aimed to determine the prevalence, risk factors, and clinical features of ACO because there are limited national data in Türkiye. Materials and Methods: The study was conducted in a cross-sectional design in nine tertiary-care hospitals. The patients followed with a diagnosis of asth- ma or COPD for at least one year were enrolled in the study. The frequency of ACO and the characteristics of the patients were evaluated in the asthma and COPD groups. Results: The study included 408 subjects (F/M= 205/203, mean age= 56.24 ± 11.85 years). The overall prevalence of ACO in both groups was 20.8% (n= 85). The frequency was higher in the COPD group than in the asthma group (n= 55; 33.3% vs. n= 22; 9.8%), respectively (p= 0.001). Patients with ACO had similarities to patients with COPD in terms of advanced age, sex, smoking, exposure to biomass during childhood, being born in rural areas, and radio- logic features. Characteristics such as a history of childhood asthma and allergic rhinitis, presence of chronic sinusitis, NSAID hypersensitivity, atopy, and high eosinophil counts were similar to those of patients with asthma (p< 0.001). The annual decline in FEV 1 was more prominent in the ACO group (mean= -250 mL) than in the asthma (mean change= -60 mL) and COPD (mean change= -230 mL) groups (p= 0.003). Conclusion: This study showed that ACO was common among patients with asthma and COPD in tertiary care clinics in our country. ACO should be considered in patients with asthma and COPD who exhibit the abovemen- tioned symptoms.
dc.identifier.DOI-ID10.5578/tt.202401886
dc.identifier.issn0494-1373
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/26386
dc.language.isoeng
dc.titleAsthma-chronic obstructive pulmonary disease overlap: Results from a national-multicenter study
dc.typeAraştırma Makalesi

Files

Collections

TR-Dizin Koleksiyonu