Acute Posterior Multifocal Placoid Pigment Epitheliopathy: A Rare Presentation of Anklylosing Spondylitis or a Paradoxical Reaction to Secukinumab?

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dc.contributor.authorAltinisik M.
dc.contributor.authorDelibay Y.
dc.contributor.authorErdogan M.
dc.date.accessioned2024-07-22T08:02:04Z
dc.date.available2024-07-22T08:02:04Z
dc.date.issued2024
dc.description.abstractPurpose: To describe an atypical presentation of acute posterior multifocal placoid pigment epitheliopathy (APMPPE) in a patient with ankylosing spondylitis (AS) receiving secukinumab. Methods: Retrospective chart review. Results: A 48-year-old female patient with AS receiving secukinumab complained of impaired vision in her left eye. Left eye examination revealed multiple yellow-white lesions at the posterior pole and central subfoveal fluid.The lesions regressed without scarring. The case was diagnosed with clinically APMPPE. Conclusion: In AS patients, posterior uveitis can manifest as APMPPE. It should be recorded as an entity to be considered in the differential diagnosis. © 2023 Taylor & Francis Group, LLC.
dc.identifier.DOI-ID10.1080/09273948.2022.2150225
dc.identifier.issn09273948
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/11693
dc.language.isoEnglish
dc.publisherTaylor and Francis Ltd.
dc.subjectAcute Disease
dc.subjectAntibodies, Monoclonal, Humanized
dc.subjectFemale
dc.subjectFluorescein Angiography
dc.subjectHumans
dc.subjectMiddle Aged
dc.subjectPigment Epithelium of Eye
dc.subjectRetrospective Studies
dc.subjectSpondylitis
dc.subjectSpondylitis, Ankylosing
dc.subjectWhite Dot Syndromes
dc.subjectetanercept
dc.subjectHLA B27 antigen
dc.subjectinfliximab
dc.subjectmethotrexate
dc.subjectsecukinumab
dc.subjectsteroid
dc.subjectmonoclonal antibody
dc.subjectsecukinumab
dc.subjectacute posterior multifocal placoid pigment epitheliopathy
dc.subjectadult
dc.subjectankylosing spondylitis
dc.subjectautofluorescence
dc.subjectbest corrected visual acuity
dc.subjectblurred vision
dc.subjectcase report
dc.subjectclinical article
dc.subjectdifferential diagnosis
dc.subjectdrug withdrawal
dc.subjecteye
dc.subjecteye examination
dc.subjectfemale
dc.subjectfluorescence angiography
dc.subjectgenetic screening
dc.subjecthuman
dc.subjectintraocular pressure
dc.subjectLetter
dc.subjectmiddle aged
dc.subjectmultimodal imaging
dc.subjectoptical coherence tomography
dc.subjectretrospective study
dc.subjectsubretinal fluid
dc.subjectthorax radiography
dc.subjectuveitis
dc.subjectvisual impairment
dc.subjectacute disease
dc.subjectankylosing spondylitis
dc.subjectpathology
dc.subjectpigment epithelium
dc.subjectspondylitis
dc.subjectwhite dot syndrome
dc.titleAcute Posterior Multifocal Placoid Pigment Epitheliopathy: A Rare Presentation of Anklylosing Spondylitis or a Paradoxical Reaction to Secukinumab?
dc.typeLetter

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