Comparison of high-sensitivity C-reactive protein and fetuin-A levels before and after treatment for subjects with subclinical hyperthyroidism

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dc.contributor.authorBilgir, O
dc.contributor.authorBilgir, F
dc.contributor.authorTopcuoglu, T
dc.contributor.authorCalan, M
dc.contributor.authorCalan, O
dc.date.accessioned2024-07-18T12:05:23Z
dc.date.available2024-07-18T12:05:23Z
dc.description.abstractThis study was designed to show the effect of propylthiouracil treatment on sCD40L, high-sensitivity C-reactive protein, and fetuin-A levels on subjects with subclinical hyperthyroidism. After checking sCD40L, high-sensitivity C-reactive protein, and fetuin-A levels of 35 patients with subclinical hyperthyroidism, each was given 50 mg tablets of propylthiouracil three times daily. After 3 months, sCD40L, high-sensitivity C-reactive protein, and fetuin-A levels were then compared to the levels before treatment. Although high-sensitivity C-reactive protein and sCD40L levels were normal in the subclinical hyperthyroidism patients compared to the healthy controls, fetuin-A levels were statistically significantly higher (*p = 0.022). After treatment, fetuin-A levels of subclinical hyperthyroidism patients decreased statistically significantly compared to the levels before treatment (**p = 0.026). sCD40L and high-sensitivity C-reactive protein levels did not have a statistically significant difference compared to the control group and post-propylthiouracil treatment. In subclinical hyperthyroidism patients, high fetuin-A levels before propylthiouracil treatment and decreases in these levels after treatment in cases with subclinical hyperthyroidism indicated the possibility of preventing long-term cardiac complications with propylthiouracil treatment.
dc.identifier.issn1355-008X
dc.identifier.other1559-0100
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/9727
dc.language.isoEnglish
dc.publisherSPRINGER
dc.subjectCORONARY-HEART-DISEASE
dc.subjectALL-CAUSE MORTALITY
dc.subjectTHYROID-DYSFUNCTION
dc.subjectBLOOD-PRESSURE
dc.subjectRISK
dc.subjectHORMONE
dc.subjectMETAANALYSIS
dc.subjectASSOCIATION
dc.subjectCOMMUNITY
dc.titleComparison of high-sensitivity C-reactive protein and fetuin-A levels before and after treatment for subjects with subclinical hyperthyroidism
dc.typeArticle

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