Synthesis and some reactions of 4-(ethoxycarbonyl)-1,5-diphenyl- 1H-pyrazole-3-carboxylic acid
| dc.contributor.author | Şener A. | |
| dc.contributor.author | Tozlu I. | |
| dc.contributor.author | Genç H. | |
| dc.contributor.author | Bildirici I. | |
| dc.contributor.author | Arisoy K. | |
| dc.date.accessioned | 2025-04-10T11:16:51Z | |
| dc.date.available | 2025-04-10T11:16:51Z | |
| dc.date.issued | 2007 | |
| dc.description.abstract | (Chemical Equation Presented) 1,5-Diphenyl-1H-pyrazole-3,4-dicarboxylic acid-4-ethyl ester 2, obtained from the 4-ethoxycarbonyl-5-phenyl-2,3-furandione 1 and N-benzylidene-N1-phenyl hydrazine, was converted via reactions of its acid chloride 3 with various alcohols or N-nucleophiles into the corresponding ester 5 or amide derivatives 6, respectively. In addition, 2 was decarboxylated to give ethyl 1,5-diphenylpyrazole-4-carboxylate 4. Nitrile 7 derivative of 2 was also obtained by dehydration of 6a in a mixture of SOCl 2 and DMF. While cyclocondensation reaction of 2 with hydrazine hydrate leads to the formation of pyrazolo[3,4-d]pyridazine-4,7-dione 8, the reaction of 3 with anhydrous hydrazine provided a new bis pyrazole derivative 9. | |
| dc.identifier.DOI-ID | 10.1002/jhet.5570440516 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.14701/52143 | |
| dc.publisher | HeteroCorporation | |
| dc.title | Synthesis and some reactions of 4-(ethoxycarbonyl)-1,5-diphenyl- 1H-pyrazole-3-carboxylic acid | |
| dc.type | Article |