Molecular Epidemiology of Hepatitis B Virus

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dc.contributor.authorArikan, A
dc.contributor.authorSanlidag, T
dc.date.accessioned2024-07-18T11:51:13Z
dc.date.available2024-07-18T11:51:13Z
dc.description.abstractIn addition to high viral copy number during replication, HBV reverse transciptase also does not have a proofreading function, therefore, many HBV genotypes, subgenotypes, mutants and recombinants can emerge. To date, 10 HBV genotypes (A-J) and almost 40 subgenotypes have been identified. Genotype A is dominant in Northwest Europe, North America and Africa; genotype B and C are common in Asian countries; genotype C is more dominant in East and Southeast Asian countries. Genotype D is widespread in the whole world and is endemic in the Meditteranean area, the Middle East and Western Asia. Genotype E is dominant in Western Africa and genotype H has been found in Central and South America. Genotype G has been reported in France, Germany and America. The genotype H is found in Central America. Recently identified genotype I, a recombination of genotypes A, C and G, was isolated in Vietnam and Laos. The most recent genotype J was identified in the Ryukyu islands in Japan and this genotype has a relationship between gibon/orangutan genotypes and human genotype C. In this review, HBV genotypes and subgenotypes, their geographic distributions and clinical aspects were overviewed.
dc.identifier.issn1301-143X
dc.identifier.other1309-1484
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/4678
dc.language.isoTurkish
dc.publisherAVES
dc.subjectCLINICAL-IMPLICATIONS
dc.subjectHBV GENOTYPES
dc.subjectMUTATIONS
dc.subjectINFECTION
dc.subjectTURKEY
dc.subjectTHERAPY
dc.subjectRISK
dc.titleMolecular Epidemiology of Hepatitis B Virus
dc.typeReview

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