Upper gastrointestinal endoscopy findings of patients with B12 deficiency

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2017

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Purpose: Vitamin B12 deficiency is highly prevalent. It may be caused by malabsorption or low intake and may trigger macrocytic anemia, neuropsychiatric and clinical symptoms. We aimed to detect the endoscopic evidence for vitamin B12 deficiency in the patients who referred to our clinic.Material and Methods: We retrospectively scanned the patients referred to Celal Bayar University, Faculty of Medicine, Department of Gastroenterology for vitamin B12 deficiency and underwent upper gastrointestinal endoscopy for this reason from May 2014 to May 2016. We examined all other reasons that might cause vitamin B12 deficiency for all patients and excluded those with other pathologies or receiving medication.Results: The patients’ mean age was 48.13 and 56.7% of them were female. The control group had a mean age of 48.6. The control group had a mean age of 48.6. Of the patients with vitamin B12 deficiency, 24.3% had no pathology in the stomach or duodenum, while 86.4% presented no pathology in the duodenum. Thirty-four percent of the control group had no pathology in the stomach or duodenum. Eighty-two percent of the cases presented normal duodenal endoscopy findings.Conclusion: Vitamin B12 deficiency is a highly prevalent pathology that may lead to a series of clinical symptoms including neuropsychiatric and hematological symptoms. Treatment provides a notably positive response, and its etiology is important for treatment. The present study found no significant difference between the age- and gender-relevant control group and the patient group in terms of gastritis and duodenal pathologies.

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