Portable quantification of silver ion by using personal glucose meter (PGM) and magnetite cross-linked invertase aggregates (MCLIA)

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dc.contributor.authorPolatoğlu İ.
dc.contributor.authorYardım A.
dc.date.accessioned2024-07-22T08:04:31Z
dc.date.available2024-07-22T08:04:31Z
dc.date.issued2022
dc.description.abstractHeavy metal detection is critical due to its harmful effects on human health and the ecosystem. Enzyme-based platforms attract attention for heavy metal detection such as silver, a toxic metal, due to being small, portable, and requiring only essential equipment compared with the basic analytical methods. In this study, magnetic cross-linked invertase aggregates (MCLIA) were developed for the first time as an enzyme-based signaling platform to detect Ag+ using a personal glucose meter (PGM). EDX, FTIR, and VSM results depicted that MCLIA was successfully developed and exhibits super-paramagnetism. In addition, MCLIA selectively detected the Ag+ at a sensitivity of 1.2 inhibition rate/μM in a linear range from 5 to 70 μM with a detection limit of 4.6 μM and IC50 value of 42.3 μM. These findings strongly indicate that MCLIA is applicable as a signal platform for portable quantification of other analytes that inhibits the invertase enzyme. © 2021 Elsevier Inc.
dc.identifier.DOI-ID10.1016/j.ab.2021.114527
dc.identifier.issn00032697
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/12731
dc.language.isoEnglish
dc.publisherAcademic Press Inc.
dc.subjectBiosensing Techniques
dc.subjectBlood Glucose Self-Monitoring
dc.subjectGlucose Oxidase
dc.subjectIons
dc.subjectSilver
dc.subjectAggregates
dc.subjectChemical detection
dc.subjectEnzyme inhibition
dc.subjectMagnetite
dc.subjectMetal ions
dc.subjectSilver
dc.subjectcobalt
dc.subjectcopper
dc.subjectmagnetite nanoparticle
dc.subjectnickel
dc.subjectsilver
dc.subjectzinc
dc.subjectglucose oxidase
dc.subjection
dc.subjectsilver
dc.subjectAg +
dc.subjectAg+ detection
dc.subjectEnzyme aggregate
dc.subjectHarmful effects
dc.subjectHeavy metals detection
dc.subjectHuman health
dc.subjectInvertase inhibition
dc.subjectPersonal glucose meter
dc.subjectPortable quantification
dc.subjectSilver ions
dc.subjectanalytic method
dc.subjectanalytical parameters
dc.subjectArticle
dc.subjectcalibration curve
dc.subjectchemical composition
dc.subjectchemical structure
dc.subjectenergy dispersive X ray spectroscopy
dc.subjectenzyme activity
dc.subjectenzyme inhibition
dc.subjectFourier transform infrared spectroscopy
dc.subjectIC50
dc.subjectimmobilization
dc.subjectlimit of detection
dc.subjectlinearity
dc.subjectmagnetite cross linked invertase aggregate method
dc.subjectscanning electron microscopy
dc.subjectsensitivity
dc.subjectvibrating sample magnetometry
dc.subjectblood glucose monitoring
dc.subjectgenetic procedures
dc.subjectmetabolism
dc.subjectGlucose
dc.titlePortable quantification of silver ion by using personal glucose meter (PGM) and magnetite cross-linked invertase aggregates (MCLIA)
dc.typeArticle

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