Asthma phenotypes in Turkey: a multicenter cross-sectional study in adult asthmatics; PHENOTURK study

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dc.contributor.authorYildiz, F
dc.contributor.authorMungan, D
dc.contributor.authorGemicioglu, B
dc.contributor.authorYorgancioglu, A
dc.contributor.authorDursun, B
dc.contributor.authorErkekol, FO
dc.contributor.authorOgus, C
dc.contributor.authorTurktas, H
dc.contributor.authorBogatekin, G
dc.contributor.authorTopcu, F
dc.contributor.authorDeveci, F
dc.contributor.authorBayram, H
dc.contributor.authorTor, M
dc.contributor.authorKalyoncu, AF
dc.date.accessioned2024-07-18T12:08:07Z
dc.date.available2024-07-18T12:08:07Z
dc.description.abstractBackground and AimsTo evaluate asthma phenotypes in patients with asthma from different regions of Turkey. MethodsA total of 1400 adult asthmatic patients (mean (SD) age: 44.0 (13.9) years, 75% females) from 14 centers across Turkey were included in this study and a standard questionnaire was applied between the time period of February 2011-January 2012. ResultsThe disease onset40 years of age was higher percentage in obese vs. normal/overweight patients and nonallergic vs. allergic patients (P<0.01). The percentage of patients who had FEV1 values over 80% was higher in allergic than nonallergic and normal/overweight than obese patients (P<0.01). Uncontrolled asthmatics have more severe disease (P<0.01). There were more frequent hospital admissions in nonallergic and uncontrolled asthmatics (P<0.01). Chronic rhino-sinusitis was the leading comorbid disorder in normal/overweight and allergic asthma, while gastroesophageal reflux disorder was more frequent in nonallergic and uncontrolled asthma (P<0.01). Asthma control rate was the highest (39.0%) in patients from Marmara region among all geographical regions (P<0.05). ConclusionIn conclusion, our findings revealed existence of clinical/trigger related phenotypes based on BMI, allergic status, control level and geographical region with more frequent respiratory dysfunction and/or adverse health outcomes in uncontrolled, obese and nonallergic phenotypes.
dc.identifier.issn1752-6981
dc.identifier.other1752-699X
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/10794
dc.language.isoEnglish
dc.publisherWILEY
dc.subjectLUNG
dc.titleAsthma phenotypes in Turkey: a multicenter cross-sectional study in adult asthmatics; PHENOTURK study
dc.typeArticle

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