Investigation of inducible clindamycin resistance among clinical isolates of staphylococci

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dc.contributor.authorGunduz, T
dc.contributor.authorAkgul, S
dc.contributor.authorOzcolpan, G
dc.contributor.authorLimoncu, ME
dc.date.accessioned2024-07-18T11:48:48Z
dc.date.available2024-07-18T11:48:48Z
dc.description.abstractThe aim of this study was to investigate the inducible clindamycin resistance in 306 strains of staphylococci, isolated from various clinical samples over a period of two years. Inducible clindamycin resistance was investigated by D-test using clindamycin and erythromycin discs as per the CLSI guidelines. Out of 177 Staphylococcus aureus strains 53 (17.3%) were methicilline resistant S. aureus (MRSA) and 124 (40.5 %) were methicillin sensitive S. aureus (MSSA). Among the coagulase negative staphylococci, 121 (39.6%) were methicillin sensitive and 8 (2.6%) were methicillin resistant. Out of 306 clinical isolates 99 (36.4%) showed erythromycin resistance. Among the erythromycin resistant isolates 46 (46.5%) were CoNS of which 8 (15.1%) were MRCoNS and 38 (31.4%) MSCoNS. Out of thirty-one erythromycin resistant isolates 20 (6.5% of the total isolates) belonged to MLSBi phenotype, eleven isolates belonged to MLSBc phenotype. We conclude that it is necessary to perform D-test for detection of inducible clindamycin in staphylococci in routine antibiotic susceptibility testing.
dc.identifier.issn1996-0808
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/3536
dc.language.isoEnglish
dc.publisherACADEMIC JOURNALS
dc.subjectAUREUS
dc.subjectMACROLIDE
dc.subjectPREVALENCE
dc.subjectEXPRESSION
dc.subjectGENES
dc.titleInvestigation of inducible clindamycin resistance among clinical isolates of staphylococci
dc.typeArticle

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