Evaluation of Cerebral Vasomotor Reactivity by Transcranial Doppler Ultrasound in Patients with Diabetic Retinopathy

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dc.contributor.authorKula, AY
dc.contributor.authorDeniz, C
dc.contributor.authorGültekin, TÖ
dc.contributor.authorAltinisik, M
dc.contributor.authorAsil, T
dc.date.accessioned2024-07-18T12:05:30Z
dc.date.available2024-07-18T12:05:30Z
dc.description.abstractThe aim of this study was to assess the correlation between cerebral vasomotor reactivity (CVR) and the grade of diabetic retinopathy. A total of 43 diabetic patients with matched severity of diabetic retinopathy between their right and left eyes were included in this study. Diabetic retinopathy was graded in three groups. Right and left middle cerebral artery CVR was assessed by the breath-holding index (BHI) using transcranial Doppler ultrasound (TCD). The mean age of the patients was 56.51 +/- 9.34 years with a mean duration of having diabetes mellitus of 14.49 +/- 8.06 years. Diabetic retinopathy was graded as mild, moderately severe, and severe in 27.9%, 34.9%, and 37.2% of the patients, respectively. The grade of diabetic retinopathy was associated with the HbA1c level (p < .049), microalbuminuria (p < .024), and BHI (p = .001). In patients with severe diabetic retinopathy, the right-sided BHI was significantly lower as compared to those with mild or moderately severe retinopathy (p = .001 and p = .008, respectively). The left-sided BHI value in patients with severe diabetic retinopathy was significantly lower as compared to those with mild or moderately severe retinopathy (p = .001 and p = .012, respectively). In subjects with moderately severe diabetic retinopathy, both-sided BHI was significantly reduced compared to those with mild retinopathy (p = .001). Our results indicate that the grade of diabetic retinopathy was associated with impaired CVR.
dc.identifier.issn0165-8107
dc.identifier.other1744-506X
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/9803
dc.language.isoEnglish
dc.publisherTAYLOR & FRANCIS AS
dc.subjectRETINAL MICROVASCULAR ABNORMALITIES
dc.subjectIMPAIRED CEREBROVASCULAR REACTIVITY
dc.subjectATHEROSCLEROSIS RISK
dc.subjectBLOOD-FLOW
dc.subjectARTERY-DISEASE
dc.subjectSTROKE
dc.subjectHEMODYNAMICS
dc.subjectMECHANISMS
dc.subjectINFARCTION
dc.subjectAGE
dc.titleEvaluation of Cerebral Vasomotor Reactivity by Transcranial Doppler Ultrasound in Patients with Diabetic Retinopathy
dc.typeArticle

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