Acoustic actuation of in situ fabricated artificial cilia

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dc.contributor.authorOrbay, S
dc.contributor.authorOzcelik, A
dc.contributor.authorBachman, H
dc.contributor.authorHuang, TJ
dc.date.accessioned2024-07-18T12:03:27Z
dc.date.available2024-07-18T12:03:27Z
dc.description.abstractWe present on-chip acoustic actuation of in situ fabricated artificial cilia. Arrays of cilia structures are UV polymerized inside a microfluidic channel using a photocurable polyethylene glycol (PEG) polymer solution and photomasks. During polymerization, cilia structures are attached to a silane treated glass surface inside the microchannel. Then, the cilia structures are actuated using acoustic vibrations at 4.6 kHz generated by piezo transducers. As a demonstration of a practical application, DI water and fluorescein dye solutions are mixed inside a microfluidic channel. Using pulses of acoustic excitations, and locally fabricated cilia structures within a certain region of the microchannel, a waveform of mixing behavior is obtained. This result illustrates one potential application wherein researchers can achieve spatiotemporal control of biological microenvironments in cell stimulation studies. These acoustically actuated, in situ fabricated, cilia structures can be used in many on-chip applications in biological, chemical and engineering studies.
dc.identifier.issn0960-1317
dc.identifier.other1361-6439
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/9132
dc.language.isoEnglish
dc.publisherIOP PUBLISHING LTD
dc.subjectBIOMIMETIC CILIA
dc.subjectDRIVEN MICROFILAMENTS
dc.subjectSEQUENTIAL INJECTION
dc.subjectSYNTHETIC CILIA
dc.subjectMOTION
dc.subjectARRAYS
dc.subjectQUANTIFICATION
dc.subjectMICROFLUIDICS
dc.subjectMICROMIXER
dc.subjectBIOMARKERS
dc.titleAcoustic actuation of in situ fabricated artificial cilia
dc.typeArticle

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