A Neuroblastoma Case Presenting with Seizures Resistant to Anti-Epileptic Treatments

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dc.contributor.authorçisil çerçi kubur
dc.contributor.authorSibğatullah Ali ORAK
dc.contributor.authorASLI KUBRA ATASEVER
dc.contributor.authorCelil Yılmaz
dc.contributor.authorMUZAFFER POLAT
dc.date.accessioned2025-04-14T05:52:42Z
dc.date.available2025-04-14T05:52:42Z
dc.date.issued2022
dc.description.abstractSeizure is a rare symptom of paraneoplastic syndrome seen in neuroblastoma without a previous history. A 4-month-old male patient who was followed up with a preliminary diagnosis of an adrenal mass in pediatric oncology was admitted to hospital with a seizure. A diagnosis of undifferentiated neuroblastoma was made with a biopsy from an adrenal mass. Seizures were resistant to anti-epileptic therapy and they were completely under control with steroids on the 4th day of treatment. Electroencephalography (EEG) disturbances disappeared and no neurologic deficit was detected. This case, which presented with isolated seizure symptoms of neuroblastoma and was treated with steroids, was a very rare presentation in which symptoms and EEG disturbances disappeared. In neuroblastoma, autoimmunity may be involved in the pathogenesis of seizures, which is a rare finding of paraneoplastic syndrome and the option of immunotherapy should be considered.
dc.identifier.DOI-ID10.4274/jpr.galenos.2022.88896
dc.identifier.urihttp://hdl.handle.net/20.500.14701/55515
dc.language.isoİngilizce
dc.subjectPatoloji
dc.subjectNörolojik Bilimler
dc.subjectOnkoloji
dc.subjectPediatri
dc.titleA Neuroblastoma Case Presenting with Seizures Resistant to Anti-Epileptic Treatments

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