The relationship of plasma zinc to lymphocyte subsets in children with chronic upper respiratory tract infections
| dc.contributor.author | Oksel F. | |
| dc.contributor.author | Tanell B. | |
| dc.date.accessioned | 2025-04-10T11:18:32Z | |
| dc.date.available | 2025-04-10T11:18:32Z | |
| dc.date.issued | 1996 | |
| dc.description.abstract | Plasma zinc level (PZL) and peripheral blood lymphocyte subsets were simultaneously assessed in children with plasma zinc levels > 0.80 mg/L (Group I, 20 cases), and in children with plasma zinc levels < 0.70 mg/L, with chronic upper respiratory infection (Group II, 22 cases) during one of the silent periods; and before (Group III-A, 11 cases) and after (Group III-B) 2 mg/kg/30 days zinc sulphate supplementation. Among all the significant findings of Student's t-test and regression analysis, the outstanding significant differences were: 1) between T4/T8 ratios (P < .001, t = 3.469) in Groups I and II; and 2) between T4/T8 ratios (P < .011, t = 2.715) in Groups III-A and III-B. Significant polynomial parabolic relations were found 1) between T(S) counts and the PZL in Group II (P < .009, r = 0.626) and in Group III-A (P < .039, r = 0.746), respectively; and 2) between B lymphocyte (B lym) populations and the PZL in Group II (P < .002, r = 0.688) and in Group III-A (P < .020, r = 0.790) respectively. Significant multifactorial relations were found 1) between PZL-T8-B lym (P < .007, r = 0.636) in Group II and (P < .014, r = 0.812) in Group III-A (thus, low PZL affects both T8 and B lym counts); and 2) between PZL-T8-T4/TB8-B lym in Group II (P < .014, r = 0.660) and Group III-A (P < .023, r = 0.850). However, the same relations were not seen when the plasma-zinc value was normal or after zinc supplementation. We did not come across any report in the literature concerning regression analyses and curve illustrations in children with upper respiratory tract infection and low plasma zinc level. In conclusion, children with chronic upper respiratory tract infections presenting a low plasma zinc level would seem to benefit if zinc is supplemented. | |
| dc.identifier.DOI-ID | 10.1002/(SICI)1520-670X(1996)9:3<107 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.14701/53547 | |
| dc.title | The relationship of plasma zinc to lymphocyte subsets in children with chronic upper respiratory tract infections | |
| dc.type | Article |