Successful use of inhaled steroids for the management of radiation pneumonitis in an infant: Case repot; [Radyasyon pnömonisinin tedavisinde i̇nhale steroidlerin bir süt çocuǧunda başarı ile kullanımı]

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dc.contributor.authorMutafoǧlu Uysal K.
dc.contributor.authorUzuner N.
dc.contributor.authorÇetingöz R.
dc.contributor.authorÖzgüven A.A.
dc.contributor.authorBabayiǧit A.
dc.contributor.authorÖlmez D.
dc.contributor.authorGüneş D.
dc.contributor.authorOlgun N.
dc.date.accessioned2024-07-22T08:21:17Z
dc.date.available2024-07-22T08:21:17Z
dc.date.issued2010
dc.description.abstractRadiation pneumonitis and subsequent pulmonary fibrosis are among the serious complications of thoracic irradiation and can have severe implications on patients' quality of life. Systemic corticosteroids are commonly used agents to treat radiation pneumonitis. However, the potential adverse effects of systemic corticosteroids, particularly in growing children, are consid-erable. An infant with lung metastatic Ewing sarcoma developed severe radiation pneumonitis following chemoradiotherapy. Systemic prednisolone was started first. However, due to the prolonged need for corticosteroid therapy, inhaled budesonide was administered with reduced systemic corticosteroid dose in an attempt to avoid the adverse effects of systemic corticosteroid treatment. The treatment was then continued exclusively with budesonide with a good clinical response. To our knowledge, this is the first pediatric case reported to benefit from inhaled steroids for severe radiation pneumonitis. This response suggested that inhaled steroids might serve as a adjunct or even an alternative to systemic corticosteroids in radiation pneumonitis. © 2010 by Türkiye Klinikleri.
dc.identifier.DOI-ID10.5336/medsci.2008-7177
dc.identifier.issn13000292
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18552
dc.language.isoTurkish
dc.publisherTurkiye Klinikleri
dc.rightsAll Open Access; Green Open Access; Hybrid Gold Open Access
dc.subjectantibiotic agent
dc.subjectbudesonide
dc.subjectcarboplatin
dc.subjectcyclophosphamide
dc.subjectdoxorubicin
dc.subjectifosfamide
dc.subjectprednisolone
dc.subjectvincristine
dc.subjectanamnesis
dc.subjectarticle
dc.subjectcancer radiotherapy
dc.subjectcase report
dc.subjectchild
dc.subjectcomputer assisted tomography
dc.subjectdisease control
dc.subjectdrug administration route
dc.subjectdrug dose increase
dc.subjectdrug dose reduction
dc.subjectdrug efficacy
dc.subjectdrug intermittent therapy
dc.subjectEwing sarcoma
dc.subjecthuman
dc.subjectmale
dc.subjectoxygen therapy
dc.subjectpreschool child
dc.subjectradiation dose
dc.subjectradiation pneumonia
dc.subjectsteroid therapy
dc.subjectsystemic therapy
dc.subjectthorax radiography
dc.subjecttreatment duration
dc.titleSuccessful use of inhaled steroids for the management of radiation pneumonitis in an infant: Case repot; [Radyasyon pnömonisinin tedavisinde i̇nhale steroidlerin bir süt çocuǧunda başarı ile kullanımı]
dc.typeArticle

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