Destiny of airway disease: interplay between epithelial barrier and the innate immune system

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dc.contributor.authorYuksel, H
dc.contributor.authorTunca, S
dc.date.accessioned2024-07-18T11:51:06Z
dc.date.available2024-07-18T11:51:06Z
dc.description.abstractWhen the organism encounters a foreign substance, it responds with mutual and regular interactions at different stages of the immune system. In airway diseases, the first encounter is at the epithelial level, where innate immune cells and their responses form the first leg of the protective mechanism. The most important barrier for environmental damage is the epithelial barrier. However, the epithelial barrier is not just a mechanical barrier. The formation of the microbiome on the epithelium and the tolerance or intolerance to environmental factors are vital. This vital balance is maintained between the epithelial surface and the subepithelial innate immune system. This is achieved by the epithelial line, which is a mechanical and functional barrier between them. In this respect, epithelial barrier function preservation has an important role in the development and prognosis of airway disease.
dc.identifier.issn2168-8370
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/4587
dc.language.isoEnglish
dc.publisherTAYLOR & FRANCIS INC
dc.subjectALLERGIC RHINITIS
dc.subjectE-CADHERIN
dc.subjectASTHMA
dc.subjectINTEGRITY
dc.subjectPROTEINS
dc.subjectCELLS
dc.titleDestiny of airway disease: interplay between epithelial barrier and the innate immune system
dc.typeReview

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