Propolis Prevents the Effects of Chronic Alcohol Intake on Ocular Tissues

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dc.contributor.authorEmre, S
dc.contributor.authorYilmaz, Z
dc.contributor.authorÖztürk, F
dc.contributor.authorEmre, MH
dc.date.accessioned2024-07-18T12:00:45Z
dc.date.available2024-07-18T12:00:45Z
dc.description.abstractAim: This study is designed to investigate the protective effects of propolis in ocular tissues against chronic alcohol exposure. Material and Method: Wistar albino rats were used in this study. Rats were divided into 4 groups, and each group was fed a special liquid diet which contained an equal amount of calories. The control group was fed the liquid special diet without alcohol and propolis. We added propolis (150 mg/kg) to the diet of the second group. The diet of the third group contained alcohol, the concentration of which was increased progressively. The fourth group was fed a diet including propolis and alcohol. To counterbalance caloric intake, we decreased the amount of glucose in the special liquid diet for groups 3 and 4. At the end of 30 days, the animals were sacrificed and samples were kept at -80 degrees C until evaluation. Specimens were investigated by light microscopy for morphology and morphometry. Results: In the histological investigation of ocular tissues, alcohol caused an increase in thickness of the cornea and corneal epithelium compared to the control group (p < 0.05). This incremental tendency was significantly reduced by propolis, and values were very close to those of the control group (p > 0.05). Alcohol did not cause any significant alteration of rat retinal thickness. Conclusion: This study showed that propolis is highly effective against corneal edema secondary to chronic alcohol intake. Copyright (C) 2009 S. Karger AG, Basel
dc.identifier.issn0030-3747
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/7942
dc.language.isoEnglish
dc.publisherKARGER
dc.subjectOXIDATIVE STRESS
dc.subjectWATER EXTRACT
dc.subjectETHANOL
dc.subjectIMPAIRMENT
dc.subjectRABBITS
dc.subjectDAMAGE
dc.subjectRATS
dc.titlePropolis Prevents the Effects of Chronic Alcohol Intake on Ocular Tissues
dc.typeArticle

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