A multimodal ophthalmic analysis in patients with systemic sclerosis using ocular response analyzer, corneal topography and specular microscopy

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dc.contributor.authorMayali, H
dc.contributor.authorAltinisik, M
dc.contributor.authorSencan, S
dc.contributor.authorPirildar, T
dc.contributor.authorKurt, E
dc.date.accessioned2024-07-18T11:53:17Z
dc.date.available2024-07-18T11:53:17Z
dc.description.abstractPurposeTo conduct a multimodal ophthalmic evaluation of systemic sclerosis (SSc) in patients using ocular response analyzer (ORA), Pentacam, and specular microscopy (SM).MethodsThirty-one SSc patients and a group of age- and sex-matched controls were enrolled in this cross-sectional study. Corneal hysteresis (CH), corneal resistance factor (CRF), corneal-compensated intraocular pressure (IOPcc), and Goldmann-correlated IOP (IOPg) were measured with ORA. Anterior chamber depth (ACD), central corneal thickness (CCT), and corneal volume (CV) measurements were obtained using Pentacam. Corneal endothelial cell density (ECD) and CCT were evaluated by SM.ResultsSSc patients had significantly lower CH, ACD, and ECD values compared to the control group (p=0.018;<0.001;<0.001, respectively). There was no significant difference regarding CRF, IOP, CV, or CCT measurements acquired by Pentacam and SM. Regarding CCT, SM and Pentacam showed relatively better agreement in SSc patients.ConclusionsMultimodal imaging can provide more comprehensive and useful information regarding the ocular involvement of systemic diseases. The multimodal evaluation in our study demonstrated that the pathologic effects of SSc may manifest as reductions in ACD, corneal elasticity, and ECD before there are any detectable changes in corneal thickness or IOP.
dc.identifier.issn0165-5701
dc.identifier.other1573-2630
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/5476
dc.language.isoEnglish
dc.publisherSPRINGER
dc.subjectINTRAOCULAR-PRESSURE MEASUREMENT
dc.subjectBIOMECHANICAL PROPERTIES
dc.subjectTHICKNESS MEASUREMENTS
dc.subjectPREVALENCE
dc.subjectPACHYMETRY
dc.subjectABNORMALITIES
dc.subjectHYSTERESIS
dc.subjectPARAMETERS
dc.subjectGLAUCOMA
dc.subjectPENTACAM
dc.titleA multimodal ophthalmic analysis in patients with systemic sclerosis using ocular response analyzer, corneal topography and specular microscopy
dc.typeArticle

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