Antineovascular effect of α-interferon on corneal neovascularization in rats

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dc.contributor.authorÖztürk F.
dc.contributor.authorSobaci G.
dc.contributor.authorSami Ilker S.
dc.contributor.authorCan C.
dc.date.accessioned2024-07-22T08:25:32Z
dc.date.available2024-07-22T08:25:32Z
dc.date.issued2001
dc.description.abstractClinical and histologic effects of topical recombinant α-interferon (IFN), systemic IFN, topical dexamethasone, and dexamethasone plus topical IFN on corneal neovascularization in response to silver nitrate cauterization were investigated in 110 eyes of 60 Wistar rats. The eyes were evaluated according to the burn stimulus, neovascularization, and histologic inflammation grades 5 days after cauterization. Antineovascular effects of topical and systemic IFN were significantly greater than a placebo but less than dexamethasone alone or in combination with IFN.
dc.identifier.DOI-ID10.1007/s12009-001-0070-5
dc.identifier.issn15304086
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/20471
dc.language.isoEnglish
dc.subjectdexamethasone
dc.subjectplacebo
dc.subjectrecombinant alpha interferon
dc.subjectsilver nitrate
dc.subjectanimal cell
dc.subjectanimal tissue
dc.subjectarticle
dc.subjectburn
dc.subjectcauterization
dc.subjectcontrolled study
dc.subjectcornea neovascularization
dc.subjectcornea perforation
dc.subjectdrug effect
dc.subjectdrug mechanism
dc.subjectinflammation
dc.subjectnecrosis
dc.subjectnonhuman
dc.subjectrat
dc.titleAntineovascular effect of α-interferon on corneal neovascularization in rats
dc.typeArticle

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