Contribution of Advanced Magnetic Resonance Imaging Techniques in Diagnosis of Breast Lesions
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Objectives: To determine the diagnostic contribution of diffusion weighted imaging (DWI) and magnetic resonance spectroscopy (MRS) identified either with mammography, ultrasonography or conventional enhanced magnetic resonance imaging (MRI) to cases with palpable breast lesions or for routine control Design: Prospective study Setting: Department of Radiology, Celal Bayar University, Turkey Subjects and Methods: Fifty female patients who applied to the clinic between November 2009 and April 2010 with different indications were included. We applied conventional breast MRI with the routine sequences. We added DWI and BREASE (MRS). After MRI examination postprocessing applications were applied. Intervention: Analysis of contribution of advanced techniques in breast lesions diagnosis Main Outcome Measure: Determining the value of DWI and MRS of breast lesions, which may be useful in improving the specificity Results: Fifty-two breast lesions in 37 cases were evaluated. In DWI when cut off apparent coefficient diffusion (ACD) value was accepted as 1.44 x 10.3 mm(2)/sn, the sensitivity was found to be 91.3% and the specifity was 62.1% in discriminating malignant and benign lesions. When the lesions which have choline peak at 3.2 ppm were accepted as malignant and lesions which do not have choline peak were accepted as benign lesions in spectroscopic examination, the specifity was 80%, the sensitivity was 31.8%, negative predictive value (NPV) was 44.4% and positive predictive value (PPV) was found to be 70%. Conclusions: Our specifity was compatible with that in the literature but sensitivity and negative ppv were lower than reported in the literature. According to ADC values, the findings in our study were compatible with the literature.